Shimada Satoko, Gen Tokichi, Okamoto Hiroyuki
Department of General Surgery, JA Toride Medical Centre, Toride-shi, Japan.
BMJ Case Rep. 2013 Jan 17;2013:bcr0520114251. doi: 10.1136/bcr.05.2011.4251.
Malignant gastric lymphoma, accounting only for 1% of primary gastric carcinoma, is usually a diffuse large B-cell lymphoma. Toyota et al reported that 37% of gastric perforations involved malignancy, generally gastric carcinoma. Fukuda et al found that less than 5% of malignant gastric lymphomas perforate. While it is relatively well known that perforations often take place during chemotherapy, they are rare in patients not receiving chemotherapy. To our knowledge, spontaneous perforation is rare in gastric malignant lymphoma, having been reported in the Japanese literature only 26 times, including this case, in the last 25 years.
恶性胃淋巴瘤仅占原发性胃癌的1%,通常为弥漫性大B细胞淋巴瘤。丰田等人报告称,37%的胃穿孔与恶性肿瘤有关,一般为胃癌。福田等人发现,不到5%的恶性胃淋巴瘤会发生穿孔。虽然化疗期间经常发生穿孔这一点相对广为人知,但在未接受化疗的患者中穿孔很少见。据我们所知,胃恶性淋巴瘤的自发性穿孔很少见,在过去25年的日本文献中,包括本病例在内,仅报道过26次。