Baroux Noémie, Rouchon Bernard, Huon Bertrand, Germain Agnès, Meunier Jean-Michel, D'Ortenzio Eric
Infectious Diseases Epidemiology Unit, Institut Pasteur of New Caledonia, Institut Pasteur International Network, Noumea, New Caledonia.
J Paediatr Child Health. 2013 Feb;49(2):109-14. doi: 10.1111/jpc.12087. Epub 2013 Jan 25.
Despite the well-documented burden of rheumatic heart disease (RHD) in several Pacific countries, the disease is poorly understood in New Caledonia. The aim of this study was to assess the prevalence of RHD detected by echocardiographic screening in school children.
An annual RHD screening programme is conducted by the Health and Social Agency of New Caledonia for school-aged children in their fourth year of primary school. For the purpose of this study, we used data collected during this echocardiographic screening between 2008 and 2010.
Of 12,728 children screened, 50.2% were male and the mean age was 9.6 ± 0.6 years. Between 2008 and 2010, 114 children had RHD, corresponding to a prevalence of 8.9 cases per 1000 (95% confidence interval (CI) (7.3-10.6)). Prevalence of RHD was higher on the main island outside Greater Noumea (13.7 per 1000; 95% CI (9.8-17.5)) and in the outlying island groups (14.6 per 1000; 95% CI (8.4-20.9)) than in Greater Noumea (5.8 per 1000; 95% CI (4.1-7.5)). RHD was more prevalent in Melanesian children (13.5 per 1000; 95% CI (10.9-16.1)) than in European (1.8 per 1000; 95% CI (0.4-3.1)).
This study documented a high prevalence of RHD in New Caledonia, particularly in districts located outside Noumea and in children of Melanesian heritage. These results uncover a hitherto unknown burden of disease in New Caledonia and underline the importance of delivering secondary prophylaxis to reduce the prevalence of RHD.
尽管在几个太平洋国家风湿性心脏病(RHD)的负担已得到充分记录,但新喀里多尼亚对该疾病的了解却很少。本研究的目的是评估通过超声心动图筛查在学龄儿童中检测到的RHD患病率。
新喀里多尼亚卫生和社会机构为小学四年级的学龄儿童开展年度RHD筛查项目。为了本研究的目的,我们使用了2008年至2010年期间在这次超声心动图筛查中收集的数据。
在接受筛查的12728名儿童中,50.2%为男性,平均年龄为9.6±0.6岁。2008年至2010年期间,114名儿童患有RHD,患病率为每1000人中有8.9例(95%置信区间(CI)(7.3 - 10.6))。大努美阿以外的主岛(每1000人中有13.7例;95%CI(9.8 - 17.5))和外围岛屿组(每1000人中有14.6例;95%CI(8.4 - 20.9))的RHD患病率高于大努美阿(每1000人中有5.8例;95%CI(4.1 - 7.5))。RHD在美拉尼西亚儿童中(每1000人中有13.5例;95%CI(10.9 - 16.1))比在欧洲裔儿童中(每1000人中有1.8例;95%CI(0.4 - 3.1))更为普遍。
本研究记录了新喀里多尼亚RHD的高患病率,特别是在努美阿以外的地区以及美拉尼西亚血统的儿童中。这些结果揭示了新喀里多尼亚迄今为止未知的疾病负担,并强调了进行二级预防以降低RHD患病率的重要性。