Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
J Clin Sleep Med. 2013 Feb 1;9(2):135-40. doi: 10.5664/jcsm.2408.
Many studies have reported a positive association between sleep problems and suicidal ideation. Some prospective studies in the elderly have shown that insomnia is a risk factor for suicide death after controlling for other depressive symptoms. However, hypotheses to explain how this risk is mediated have not previously been assessed. We tested the hypothesis that insomnia symptoms are related to suicidal ideation through mediation by dysfunctional beliefs and attitudes about sleep and/or nightmares.
We measured symptoms of depression, hopelessness, insomnia severity, dysfunctional beliefs and attitudes about sleep, nightmares, and suicidal ideation intensity on a convenience sample of 50 patients with depressive disorders, including 23 outpatients, 16 inpatients, and 11 suicidal ED patients. Mediation analysis was used to assess the indirect effects of insomnia symptoms on suicidal ideation through dysfunctional beliefs about sleep and through nightmares.
Our findings again confirmed a positive association between insomnia symptoms and the intensity of suicidal ideas in depressed patients (b = 0.64, 95% CI = [0.14, 1.15]). However, we extended and clarified our earlier findings by now showing that dysfunctional beliefs and attitudes about sleep as well as nightmares may mediate the association between insomnia symptoms and suicidal ideation. The indirect effects of insomnia symptoms through dysfunctional beliefs about sleep and through nightmares were 0.38 (-0.03, 0.97) and 0.35 (0.05, 0.75), respectively.
Nightmares as well as dysfunctional beliefs and attitudes about sleep each are positively and independently related to the intensity of suicidal ideation, and the effect of insomnia symptoms appears to be mediated through these two variables.
许多研究报告称,睡眠问题与自杀意念之间存在正相关关系。一些针对老年人的前瞻性研究表明,在控制其他抑郁症状后,失眠是自杀死亡的一个风险因素。然而,以前尚未评估过解释这种风险如何被中介的假设。我们通过中介检验假设,即通过对睡眠和/或噩梦的不良信念和态度的中介作用,失眠症状与自杀意念有关。
我们在一个包括 23 名门诊患者、16 名住院患者和 11 名自杀 ED 患者在内的抑郁障碍便利样本中测量了抑郁、绝望、失眠严重程度、睡眠不良信念和态度、噩梦和自杀意念强度的症状。使用中介分析评估了通过睡眠不良信念和通过噩梦对失眠症状对自杀意念的间接影响。
我们的研究结果再次证实,失眠症状与抑郁患者自杀意念的强度之间存在正相关关系(b = 0.64,95%CI = [0.14, 1.15])。然而,我们通过现在表明,睡眠不良信念和态度以及噩梦可能会调节失眠症状和自杀意念之间的关联,扩展和澄清了我们早期的发现。通过睡眠不良信念和通过噩梦对失眠症状的间接影响分别为 0.38(-0.03, 0.97)和 0.35(0.05, 0.75)。
噩梦以及睡眠不良信念和态度都与自杀意念的强度呈正相关且独立相关,失眠症状的影响似乎通过这两个变量来介导。