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符合治疗标准但不符合手术要求的腹主动脉瘤的自然病程。

The natural course of abdominal aortic aneurysms that meet the treatment criteria but not the operative requirements.

机构信息

Department of Vascular Surgery, Helsinki University Central Hospital (HUCH), P.O. Box 340, 00029 HUS Helsinki, Finland.

出版信息

Eur J Vasc Endovasc Surg. 2013 Apr;45(4):326-31. doi: 10.1016/j.ejvs.2012.12.019. Epub 2013 Feb 9.

Abstract

INTRODUCTION

Abdominal aortic aneurysms (AAAs) of 55 mm diameter or growth >5 mm in 6 months are commonly accepted treatment criteria. The aim of this study was to establish the outcome of aneurysms that met the treatment criteria but not the operative requirements.

MATERIAL AND METHODS

Patients (n = 154) who were declined from operative care of AAA in Helsinki University Central Hospital (HUCH) during 2000-2010 were retrospectively analysed. Reasons for exclusion were identified. The follow-up period extended until the end of April 2012. The rupture rate and mortality were determined. The patients were analysed according to the aneurysm diameter: 55-60, 61-70 and >70 mm.

RESULTS

The reasons for exclusion from operative treatment were cardiorespiratory co-morbidities in 33%, cancer in 8%, overall condition in 33% and patient's choice in 21% of the patients. Regardless of the size of the aneurysm, the cause of death was aneurysm rupture in 43%, which was confirmed either in hospital or in autopsy for 76% of the patients. Of the ruptured aneurysms, 12 were operated of which five survived.

CONCLUSIONS

A ruptured aneurysm is the most common cause of death among patients unfit for surgery; this should be considered in the preoperative evaluation process, especially since 5 of the 12 patients survived the ruptured AAA (RAAA) operation.

摘要

介绍

直径为 55 毫米或在 6 个月内增长超过 5 毫米的腹主动脉瘤(AAA)通常被认为是治疗的标准。本研究的目的是评估符合治疗标准但不符合手术要求的动脉瘤的结果。

材料和方法

回顾性分析了 2000 年至 2010 年期间在赫尔辛基大学中心医院(HUCH)因 AAA 而被拒绝手术治疗的 154 名患者。确定了排除的原因。随访期延长至 2012 年 4 月底。确定了破裂率和死亡率。根据动脉瘤直径将患者分为三组:55-60 毫米、61-70 毫米和>70 毫米。

结果

因心肺合并症而被排除在手术治疗之外的患者占 33%,因癌症而被排除的患者占 8%,因总体状况而被排除的患者占 33%,因患者选择而被排除的患者占 21%。无论动脉瘤的大小如何,43%的死亡原因是动脉瘤破裂,其中 76%的患者在医院或尸检中得到了证实。在破裂的动脉瘤中,有 12 例接受了手术,其中 5 例存活。

结论

对于不适合手术的患者来说,破裂的动脉瘤是最常见的死亡原因;这在术前评估过程中应予以考虑,尤其是因为 12 例破裂的 AAA(RAAA)手术中有 5 例患者存活。

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