Department of Pharmacy, Grenoble University Hospital, Grenoble, France.
PLoS One. 2013;8(2):e56247. doi: 10.1371/journal.pone.0056247. Epub 2013 Feb 20.
The objective of this work was to compare two generic questionnaires assessing patients' satisfaction with medication. In addition we tested whether satisfaction can predict adherence to medication regimens in patients with chronic diseases, and which dimensions of satisfaction are most involved.
This prospective, observational study was conducted over one year in a heterogeneous population of patients with various chronic diseases. Satisfaction with medication was assessed by using the TSQM® vII and the SatMed-Q® questionnaires, and adherence to treatment was assessed with the Morisky-Green questionnaire. Clinical pharmacists interviewed patients to collect clinical, demographic and therapeutic data.
190 patients were enrolled. Both questionnaires showed excellent reliability and correlation was high (R=0.70; p<0.001). Adherence was correlated with satisfaction with medication whether assessed with the SatMed-Q® (R=0.23; p=0.002) or the TSQM® (R=0.17; p=0.02). Among different dimensions of satisfaction, convenience of use and side effects are prominent predictors of adherence.
Adherence is related to the patient's satisfaction with medication whether assessed with the TSQM® vII or the SatMed-Q®. Therefore, these simple questionnaires could be used as predictive tools to identify patients whos' adherence needs to be improved.
本研究旨在比较两种评估患者对药物治疗满意度的通用问卷。此外,我们还测试了满意度是否可以预测慢性病患者对药物治疗方案的依从性,以及哪些满意度维度与治疗依从性的关系更为密切。
本前瞻性观察性研究在一年时间内对来自不同慢性疾病患者的异质人群进行了研究。采用 TSQM® vII 和 SatMed-Q®问卷评估患者对药物的满意度,采用 Morisky-Green 问卷评估治疗依从性。临床药师通过访谈患者收集临床、人口统计学和治疗相关数据。
共纳入 190 例患者。两种问卷均具有极好的可靠性,且相关性较高(R=0.70;p<0.001)。无论使用 SatMed-Q®(R=0.23;p=0.002)还是 TSQM®(R=0.17;p=0.02)评估,治疗依从性均与对药物的满意度相关。在不同的满意度维度中,用药便利性和副作用是治疗依从性的重要预测因素。
无论使用 TSQM® vII 还是 SatMed-Q®评估,患者对药物治疗的满意度与治疗依从性相关。因此,这些简单的问卷可以作为预测工具,以识别需要提高治疗依从性的患者。