Loebe M, Ren D, Rodriguez L, La Francesca S, Bismuth J, Lumsden A
Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas.
HSR Proc Intensive Care Cardiovasc Anesth. 2012;4(4):243-50.
Acute thoracic aortic aneurysm is one of the most life-threatening vascular disorders recognized to date. The majority of these aortic ruptures rapidly end in mortality, with 50% of patients suffering death before reaching the hospital. Thus, acute management through surgical intervention is often indicated, especially in cases of ascending aortic rupture. Physical examination is critical in making the diagnosis, as clinical signs and symptoms often vary depending on the location of the dissection. Clinicians should have a low threshold for including thoracic aortic dissection in their differential diagnosis, especially when a patient presents with acute onset chest or back pain. In this report, we discuss the different categories of aortic dissections and the current treatment modalities for each. These include endovascular aortic repair, which has become a viable treatment modality in certain cases of type B dissection. Offering a less invasive approach, the technique known as thoracic endovascular repair currently affords a treatment option to a patient population who would have otherwise been deemed non-surgical candidates. Hybrid thoracic endovascular aortic repair has also become a pertinent surgical technique, and successful outcomes have been demonstrated when it is employed to repair ascending aortic aneurysms. We also describe our Acute Aortic Treatment Center, a rapid multicentric triage system for the management of acute aortic pathologies, which has resulted in significant improvements in patient outcomes.
急性胸主动脉瘤是迄今为止公认的最危及生命的血管疾病之一。这些主动脉破裂大多迅速导致死亡,50%的患者在到达医院之前就已死亡。因此,通常需要通过手术干预进行紧急处理,尤其是在升主动脉破裂的情况下。体格检查对做出诊断至关重要,因为临床体征和症状往往因夹层的位置而异。临床医生在鉴别诊断中应将胸主动脉夹层纳入考虑范围的门槛要低,特别是当患者出现急性胸痛或背痛时。在本报告中,我们讨论了主动脉夹层的不同类别以及针对每类的当前治疗方式。这些包括血管腔内主动脉修复术,它在某些B型夹层病例中已成为一种可行的治疗方式。作为一种侵入性较小的方法,称为胸主动脉腔内修复术的技术目前为那些原本会被视为非手术候选者的患者群体提供了一种治疗选择。杂交胸主动脉腔内修复术也已成为一种相关的外科技术,当用于修复升主动脉瘤时已证明有成功的结果。我们还介绍了我们的急性主动脉治疗中心,这是一个用于管理急性主动脉病变的快速多中心分诊系统,它已使患者的治疗结果有了显著改善。