抽动障碍患病率研究综述：方法学上的注意事项。
Review of prevalence studies of tic disorders: methodological caveats.
作者信息
Cubo Esther
机构信息
Neurology Department, Complejo Asistencial Universitario de Burgos, Spain.
出版信息
Tremor Other Hyperkinet Mov (N Y). 2012;2. doi: 10.7916/D8445K68. Epub 2012 May 18.
INTRODUCTION
Tic disorders are neurodevelopmental disorders of childhood associated with psychiatric comorbidity and academic problems. Estimating the prevalence and understanding the epidemiology of tic disorders is more complex than was once thought. Until fairly recently, tic disorders were thought to be rare, but today tics are believed to be the most common movement disorder, with 0.2-46.3% of schoolchildren experiencing tics during their lifetime. Tentative explanations for differing prevalence estimates include the multidimensional nature of tics with a varied and heterogeneous presentation, and the use of different epidemiological methods and study designs.
METHODS
Literature review and analysis of methodological issues pertinent to epidemiological studies of tic disorders.
RESULTS
Epidemiological studies of tic disorders were reviewed, and the main elements of epidemiological studies, including sample selection, case ascertainment strategy, definition of tic disorders, and the degree of coverage of the eligible population (i.e., the response rate) were examined.
DISCUSSION
In order to improve the quality of epidemiological studies of tic disorders, a number of recommendations were made, including but not limited to a review of the diagnostic criteria for tic disorders, and inclusion of new tic disorder categories for those with tics of secondary etiology.
引言
抽动障碍是儿童期的神经发育障碍，与精神共病和学业问题相关。估计抽动障碍的患病率并了解其流行病学情况比以往认为的更为复杂。直到最近，抽动障碍还被认为是罕见的，但如今抽动被认为是最常见的运动障碍，0.2%至46.3%的学童在其一生中会经历抽动。对患病率估计存在差异的初步解释包括抽动具有多维性质，表现多样且异质性，以及使用了不同的流行病学方法和研究设计。
方法
对与抽动障碍流行病学研究相关的方法学问题进行文献综述和分析。
结果
对抽动障碍的流行病学研究进行了综述，并检查了流行病学研究的主要要素，包括样本选择、病例确定策略、抽动障碍的定义以及符合条件人群的覆盖程度（即应答率）。
讨论
为了提高抽动障碍流行病学研究的质量，提出了一些建议，包括但不限于对抽动障碍诊断标准进行审查，以及为继发病因的抽动患者纳入新的抽动障碍类别。
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