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降主动脉瘤开放修复术。

Open repair of descending thoracic aneurysms.

作者信息

Chiesa R, Tshomba Y, Civilini E, Marone E M, Bertoglio L, Baccellieri D, Coppi G, Logaldo D, Melissano G

机构信息

Department of Vascular Surgery, Università Vita-Salute San Raffaele, Milan, Italy.

出版信息

HSR Proc Intensive Care Cardiovasc Anesth. 2010;2(3):177-90.

Abstract

INTRODUCTION

Current strategies for operative treatment of a thoracic aortic aneurysm consist of open repair with surgical graft replacement or endovascular exclusion. To reduce mortality and morbidity of open repair, a multimodal approach has gradually evolved by maximizing organ protection.

METHODS

On a total of 1108 patients treated in our Center from 1993 for pathology involving the thoracic aorta, we reviewed the prospectively collected data of 194 consecutive patients who underwent open thoracic aortic aneurysm repair, 104 (54%) for degenerative aneurysms, 65 (34%) for dissections, 25 (12%) for other pattern of disease. Left Heart Bypass was used in 82% of cases, clamp and sew technique in 16%, hypotermic circulatory arrest in 2%.

RESULTS

Overall perioperative mortality was 4.1%. The rate of pulmonary complications was 8.8%. The rate of cardiac complications, i.e. new onset myocardial necrosis demonstrated by positive blood tests, was 6.2%. The rate of renal complications was 7.2%. Cerebrovascular accident, defined as a new neurologic deficit lasting more than 24 hours confirmed by imaging, occurred in 2.0% of patients. The rate of spinal cord ischemia, manifesting either as paraplegia or paraparesis, was 4.6%.

CONCLUSIONS

Mortality and morbidity rates of open thoracic aortic aneurysm repair are currently satisfactory especially in fit patients. In order to define surgical indications and the role of endovascular repair, consideration of age of the patient, comorbidity, symptoms, life expectancy, likely quality of life (if asymptomatic), aortic diameter, aneurysm morphology, aneurysm extent, suitability of landing zones, and operator experience are all distinctly relevant.

摘要

引言

目前胸主动脉瘤的手术治疗策略包括开放性修复并置换手术移植物或血管腔内隔绝术。为降低开放性修复的死亡率和发病率,通过最大化器官保护,一种多模式方法逐渐形成。

方法

在我们中心1993年以来治疗的共1108例累及胸主动脉病变的患者中,我们回顾了194例接受开放性胸主动脉瘤修复术患者的前瞻性收集数据,其中104例(54%)为退行性动脉瘤,65例(34%)为夹层动脉瘤,25例(12%)为其他疾病类型。82%的病例使用了左心转流,16%采用钳夹缝合技术,2%采用低温循环停止。

结果

围手术期总死亡率为4.1%。肺部并发症发生率为8.8%。心脏并发症发生率,即血液检查阳性显示的新发心肌坏死,为6.2%。肾脏并发症发生率为7.2%。脑血管意外定义为影像学证实持续超过24小时的新的神经功能缺损,发生在2.0%的患者中。脊髓缺血发生率,表现为截瘫或轻截瘫,为4.6%。

结论

目前开放性胸主动脉瘤修复术的死亡率和发病率令人满意,尤其是在身体状况良好的患者中。为了确定手术指征和血管腔内修复的作用,患者年龄、合并症、症状、预期寿命、可能的生活质量(如果无症状)、主动脉直径、动脉瘤形态、动脉瘤范围、锚定区适宜性以及术者经验等因素均具有明显相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3aad/3484579/182be32ef22d/hsrp-02-177-g001.jpg

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