• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

LSD 或裸盖菇素(致幻蘑菇)的非法使用与迷幻体验呈剂量依赖性相关,但 MDMA 或非致幻药物则不然。

Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner.

机构信息

Department of Psychology, Bond University, Gold Coast Queensland 4229, Australia.

出版信息

J Psychoactive Drugs. 2012 Nov-Dec;44(5):410-7. doi: 10.1080/02791072.2012.736842.

DOI:10.1080/02791072.2012.736842
PMID:23457892
Abstract

Psychedelic drugs have long been known to be capable of inducing mystical or transcendental experiences. However, given the common "recreational" nature of much present-day psychedelic use, with typical doses tending to be lower than those commonly taken in the 1960s, the extent to which illicit use of psychedelics today is associated with mystical experiences is not known. Furthermore the mild psychedelic MDMA ("Ecstasy") is more popular today than "full" psychedelics such as LSD or psilocybin, and the contribution of illicit MDMA use to mystical experiences is not known. The present study recruited 337 adults from the website and newsletter of the Multidisciplinary Association for Psychedelic Studies (MAPS), most of whom reported use of a variety of drugs both licit and illicit including psychedelics. Although only a quarter of the sample reported "spiritual" motives for using psychedelics, use of LSD and psilocybin was significantly positively related to scores on two well-known indices of mystical experiences in a dose-related manner, whereas use of MDMA, cannabis, cocaine, opiates and alcohol was not. Results suggest that even in today's context of "recreational" drug use, psychedelics such as LSD and psilocybin, when taken at higher doses, continue to induce mystical experiences in many users.

摘要

迷幻药物长期以来被认为能够诱发神秘或超越性的体验。然而,鉴于当今大多数迷幻药物的使用通常具有“娱乐”性质,典型剂量往往低于 20 世纪 60 年代的常用剂量,因此目前非法使用迷幻药物与神秘体验之间的关联程度尚不清楚。此外,轻度迷幻剂 MDMA(“摇头丸”)比 LSD 或裸盖菇素等“全效”迷幻剂更为流行,非法使用 MDMA 对神秘体验的影响也不得而知。本研究招募了来自多学科迷幻药物研究协会(MAPS)网站和通讯的 337 名成年人,他们中的大多数人报告称使用了各种合法和非法药物,包括迷幻药物。尽管只有四分之一的样本报告称使用迷幻药物有“精神”动机,但 LSD 和裸盖菇素的使用与两个著名的神秘体验指数的得分呈正相关,且与剂量有关,而 MDMA、大麻、可卡因、阿片类药物和酒精的使用则没有。结果表明,即使在当今“娱乐”性药物使用的背景下,LSD 和裸盖菇素等迷幻药物在较高剂量下仍会在许多使用者中引发神秘体验。

相似文献

1
Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner.LSD 或裸盖菇素(致幻蘑菇)的非法使用与迷幻体验呈剂量依赖性相关,但 MDMA 或非致幻药物则不然。
J Psychoactive Drugs. 2012 Nov-Dec;44(5):410-7. doi: 10.1080/02791072.2012.736842.
2
Alterations of consciousness and mystical-type experiences after acute LSD in humans.人类急性服用麦角酸二乙酰胺(LSD)后意识的改变及神秘主义类型的体验。
Psychopharmacology (Berl). 2017 May;234(9-10):1499-1510. doi: 10.1007/s00213-016-4453-0. Epub 2016 Oct 7.
3
MDMA/ecstasy use and psilocybin use are associated with lowered odds of psychological distress and suicidal thoughts in a sample of US adults.在一项美国成年人样本中,使用 MDMA/摇头丸和使用裸盖菇素与降低心理困扰和自杀念头的几率有关。
J Psychopharmacol. 2022 Jan;36(1):46-56. doi: 10.1177/02698811211058923. Epub 2022 Jan 5.
4
Development of the Psychological Insight Questionnaire among a sample of people who have consumed psilocybin or LSD.心理洞察问卷在使用裸盖菇素或 LSD 的人群样本中的发展。
J Psychopharmacol. 2021 Apr;35(4):437-446. doi: 10.1177/0269881120967878. Epub 2021 Jan 9.
5
Naturalistic psychedelic therapy: The role of relaxation and subjective drug effects in antidepressant response.自然主义致幻剂疗法:放松和主观药物效应在抗抑郁反应中的作用。
J Psychopharmacol. 2024 Oct;38(10):873-886. doi: 10.1177/02698811241278873. Epub 2024 Sep 20.
6
Cessation and reduction in alcohol consumption and misuse after psychedelic use.使用迷幻药物后停止和减少酒精消费和滥用。
J Psychopharmacol. 2019 Sep;33(9):1088-1101. doi: 10.1177/0269881119845793. Epub 2019 May 14.
7
Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function.经典迷幻剂:流行病学、治疗学、神秘体验和大脑网络功能的综合综述。
Pharmacol Ther. 2019 May;197:83-102. doi: 10.1016/j.pharmthera.2018.11.010. Epub 2018 Dec 4.
8
High dose psilocybin is associated with positive subjective effects in healthy volunteers.高剂量裸盖菇素与健康志愿者的积极主观效应有关。
J Psychopharmacol. 2018 Jul;32(7):770-778. doi: 10.1177/0269881118780713. Epub 2018 Jun 27.
9
Acute subjective effects in LSD- and MDMA-assisted psychotherapy.LSD 和 MDMA 辅助心理治疗中的急性主观效应。
J Psychopharmacol. 2021 Apr;35(4):362-374. doi: 10.1177/0269881120959604. Epub 2020 Oct 8.
10
Lifetime use of MDMA/ecstasy and psilocybin is associated with reduced odds of major depressive episodes.终生使用 MDMA/摇头丸和裸盖菇素与降低重度抑郁发作的几率有关。
J Psychopharmacol. 2022 Jan;36(1):57-65. doi: 10.1177/02698811211066714. Epub 2022 Jan 5.

引用本文的文献

1
The Mystical Experience Questionnaire 4-Item and Challenging Experience Questionnaire 7-Item.神秘体验问卷(4项)和挑战性体验问卷(7项)。
Psychedelic Med (New Rochelle). 2024 Mar 12;2(1):33-43. doi: 10.1089/psymed.2023.0046. eCollection 2024 Mar.
2
Validation of the imperial psychedelic predictor scale.帝国迷幻预测量表的验证
Psychol Med. 2024 Sep 27;54(12):1-9. doi: 10.1017/S0033291724002204.
3
Effect of MDMA-assisted therapy on mood and anxiety symptoms in advanced-stage cancer (EMMAC): study protocol for a double-blind, randomised controlled trial.
MDMA 辅助治疗对晚期癌症患者情绪和焦虑症状的影响(EMMAC):一项双盲、随机对照试验的研究方案。
Trials. 2024 May 21;25(1):336. doi: 10.1186/s13063-024-08174-x.
4
Development of the Japanese version of the Ego-Dissolution Inventory (EDI).自我解体量表(EDI)日文版的开发。
Neuropsychopharmacol Rep. 2024 Mar;44(1):292-297. doi: 10.1002/npr2.12419. Epub 2024 Feb 6.
5
Psychedelic-Assisted Therapy in Military and Veterans Healthcare Systems: Clinical, Legal, and Implementation Considerations.致幻剂辅助治疗在军事和退伍军人医疗保健系统中的应用:临床、法律和实施方面的考虑。
Curr Psychiatry Rep. 2023 Oct;25(10):513-532. doi: 10.1007/s11920-023-01446-4. Epub 2023 Sep 8.
6
Psilocybin as a Treatment for Psychiatric Illness: A Meta-Analysis.裸盖菇素作为精神疾病的一种治疗方法:一项荟萃分析。
Cureus. 2022 Nov 22;14(11):e31796. doi: 10.7759/cureus.31796. eCollection 2022 Nov.
7
Lower-dose psycholytic therapy - A neglected approach.低剂量精神olytic疗法——一种被忽视的方法。 (注:原文中“psycholytic”可能有误,推测正确的词可能是“psycholytic”,但按给定原文准确翻译如此)
Front Psychiatry. 2022 Dec 2;13:1020505. doi: 10.3389/fpsyt.2022.1020505. eCollection 2022.
8
Facing death, returning to life: A qualitative analysis of MDMA-assisted therapy for anxiety associated with life-threatening illness.直面死亡,重获新生:对3,4-亚甲基二氧甲基苯丙胺辅助治疗危及生命疾病相关焦虑症的定性分析
Front Psychiatry. 2022 Sep 27;13:944849. doi: 10.3389/fpsyt.2022.944849. eCollection 2022.
9
Validation of the .验证.
Subst Use Misuse. 2022;57(13):1961-1972. doi: 10.1080/10826084.2022.2125269. Epub 2022 Sep 21.
10
Meta-analysis of associations between empathy and alcohol use and problems in clinical and non-clinical samples.元分析临床和非临床样本中同理心与酒精使用和问题之间的关联。
Addiction. 2022 Nov;117(11):2793-2804. doi: 10.1111/add.15941. Epub 2022 May 29.