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双支右冠状动脉及其临床意义。

Double right coronary artery and its clinical implications.

作者信息

Chien Tsu-Ming, Chen Chih-Wei, Chen Huai-Min, Lee Chee-Siong, Lin Ching-Cheng, Chen Ying-Fu

机构信息

1 Department of General Medicine, Chi Mei Medical Center, Tainan, Taiwan.

2 School of Medicine, Chung Shan Medical University, Taichung, Taiwan.

出版信息

Cardiol Young. 2014 Feb;24(1):5-12. doi: 10.1017/S1047951113000176. Epub 2013 Mar 5.

Abstract

Congenital anomalies of the coronary arteries are present in 0.2-1.4% of the general population. These anomalies represent one of the most confusing issues in the field of cardiology and challenges for interventional cardiologists and cardiac surgeons if the anomalies are unrecognised. Double right coronary artery is one of the rarest coronary arteries. Previously, the probability of developing atherosclerotic changes in patients with a double right coronary artery was considered to be equal to that in those without it. In reality, however, a high prevalence of atherosclerotic coronary artery disease was found in patients with a double right coronary artery originating from a single ostium after our comprehensive literature search through the PubMed database. Owing to the fact that double right coronary artery is both a congenital and potentially atherosclerotic coronary artery disease at diagnosis, coronary intervention or cardiac operation is more complicated than previously believed. Individuals with a double right coronary artery may be unaware of its presence until an accidental finding during coronary angiography or cardiac operation and are at risk for unsuspected complications of atherosclerotic coronary artery disease or during cardiac operation. Therefore, it is important to obtain information on the anatomic variants of this congenital coronary anomaly in patients who are undergoing either coronary intervention, aortic root operation or myocardial revascularisation. To our knowledge, this is the first comprehensive article to discuss the anomalies and their clinical implications.

摘要

先天性冠状动脉异常在普通人群中的发生率为0.2% - 1.4%。这些异常是心脏病学领域最令人困惑的问题之一,对于介入心脏病学家和心脏外科医生来说,如果未能识别这些异常,将会构成挑战。双右冠状动脉是最罕见的冠状动脉类型之一。以前,人们认为双右冠状动脉患者发生动脉粥样硬化改变的概率与无此异常的患者相同。然而,通过对PubMed数据库进行全面的文献检索,我们发现单开口起源的双右冠状动脉患者中,冠状动脉粥样硬化性疾病的患病率很高。由于双右冠状动脉在诊断时既是一种先天性疾病,又可能是动脉粥样硬化性冠状动脉疾病,因此冠状动脉介入治疗或心脏手术比以前认为的更为复杂。双右冠状动脉患者可能直到冠状动脉造影或心脏手术时偶然发现才知道自己有这种情况,并且有发生动脉粥样硬化性冠状动脉疾病意外并发症或心脏手术期间并发症的风险。因此,对于接受冠状动脉介入治疗、主动脉根部手术或心肌血运重建的患者,了解这种先天性冠状动脉异常的解剖变异情况非常重要。据我们所知,这是第一篇全面讨论这些异常及其临床意义的文章。

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