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肾上腺神经母细胞瘤与川崎病并存:1例罕见病例报告

Concurrent adrenal neuroblastoma and kawasaki disease: a report of a rare case.

作者信息

Alavi Samin, Fahimzad Alireza, Jadali Farzaneh, Ghazizadeh Farid, Rashidi Armin

机构信息

Pediatric Congenital Hematologic Disorders Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Case Rep Pediatr. 2013;2013:931703. doi: 10.1155/2013/931703. Epub 2013 Feb 6.

Abstract

Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and a leading cause of acquired heart disease. It is assumed that there is an activation of the immune system by an infectious trigger in a genetically susceptible host. Neuroblastoma is the most common extracranial solid tumor in young children. It mainly originates from primordial neural crest cells that generate the adrenal medulla and sympathetic ganglia. A diagnosis of concurrent KD and neuroblastoma in a living child has been made in only one previous report. We report the second case and review the literature.

摘要

川崎病(KD)是一种病因不明的全身性血管炎,是后天性心脏病的主要病因。据推测,在遗传易感宿主中,感染触发因素会激活免疫系统。神经母细胞瘤是幼儿最常见的颅外实体瘤。它主要起源于产生肾上腺髓质和交感神经节的原始神经嵴细胞。此前仅有一份报告记录了一名在世儿童同时患有川崎病和神经母细胞瘤的病例。我们报告第二例病例并回顾相关文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c37/3580901/80889b281b86/CRIM.PEDIATRICS2013-931703.001.jpg

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