Miller Benjamin R, Troyer Melissa, Busey Thomas
Department of Psychological and Brain Sciences ; Program in Neuroscience.
J Undergrad Neurosci Educ. 2008 Fall;7(1):A19-25. Epub 2008 Oct 15.
A current topic in neuroscience addresses the link between brain activity and visual awareness. The electroencephalogram (EEG), which uses non-invasive high temporal resolution scalp recordings to measure brain activity, is a common tool used to probe this question. EEG recordings, however, are difficult to implement in the curriculum of laboratory-based courses. Thus, undergraduate students often lack experience with EEG experiments. We report here an EEG program (Virtual EEG) that can be used in undergraduate courses to analyze averaged EEG data, termed Event Related Potentials (ERPs). The program was designed so that students can generate hypothesis-driven studies that address how the brain encodes categories of visual stimuli. The Virtual EEG is a large database of EEG recordings consisting of 32 channels taken from real human subjects who were shown 256 pictures of visual stimuli. The program provides a number of possible ways to group the stimuli. After selecting the appropriate stimuli, the program constructs graphs of the ERPs. The channels can be selected for statistical analysis. Because the program uses real data, students are encouraged to interpret their results in light of previously published work. Thus, students have the opportunity to discover something new about how the brain processes visual information. This article also includes a tutorial and summarizes the results of an assessment survey. Finally, we include information regarding the companion Virtual EEG website. The Virtual EEG has been used successfully for the past six years at Indiana University with over a thousand undergraduate students in a research methods course, and the assessment results illustrate its strengths and limitations.
神经科学领域当前的一个热门话题是探讨大脑活动与视觉意识之间的联系。脑电图(EEG)通过非侵入性的高时间分辨率头皮记录来测量大脑活动,是用于探究这个问题的常用工具。然而,EEG记录在基于实验室的课程教学中难以实施。因此,本科生往往缺乏EEG实验的经验。我们在此报告一个EEG程序(虚拟EEG),它可用于本科课程,以分析平均EEG数据,即事件相关电位(ERP)。该程序的设计目的是让学生能够开展基于假设的研究,以探讨大脑如何对视觉刺激类别进行编码。虚拟EEG是一个大型EEG记录数据库,包含从实际人类受试者身上采集的32个通道的数据,这些受试者观看了256张视觉刺激图片。该程序提供了多种对刺激进行分组的可能方式。在选择合适的刺激后,程序会构建ERP图表。可以选择通道进行统计分析。由于该程序使用的是真实数据,我们鼓励学生参照先前发表的研究成果来解读他们的结果。这样,学生就有机会发现大脑处理视觉信息方面的新内容。本文还包括一个教程,并总结了一项评估调查的结果。最后,我们提供了有关配套的虚拟EEG网站的信息。在过去六年里,印第安纳大学已成功将虚拟EEG用于研究方法课程,一千多名本科生参与其中,评估结果显示了它的优势与不足。