Department of Surgery, College of Medicine, King Faisal University & King Fahd Hospital, Al- Ahsa, KSA.
World J Emerg Surg. 2013 Mar 8;8(1):10. doi: 10.1186/1749-7922-8-10.
BACKGROUND/ PURPOSE: Perforated peptic ulcer (PPU) is still an existing disease that occurs frequently in the 21st century despite of the wide availability of antiulcer medication and Helicobacter eradication. The current study aimed to evaluate the hypothesis that its outcome might be improved by using the laparoscopy. The outcome of treatment in terms of complications, mortality and hospital stay with relevant to laparoscopy was analyzed.
This prospective descriptive study was carried on the period of 3 years from July 2009 till July 2012. All patients with acute abdominal pain that was clinically diagnosed as having perforated peptic ulcer were included. Excluded from this study were those patients with concomitant bleeding from the ulcer and evidence of gastric outlet obstructions. Also excluded were those with evidence of large perforation more than 10 mm and patients with symptoms of more than 36 h durations for fear of septic shock.
Forty seven patients were studied out of a total 53 PPU patients; they were 41 males and 6 females with the male to female ratio of 6.8:1. Their age ranged from 19 to 55 years with the mean age of 39.5 ± 8.6 years. Forty five patients were successfully treated by laparoscopy while only 2 cases that were early presented with signs of hypovolumic shock were converted into laparotomy due to severe bleeding. The mean hospital stay was 75 ± 12.6 h. Post operative complications included death of one patient in the postoperative period at the Intensive care unit (ICU) plus post operative fever in the 2 patients who underwent laparotomy and it was amenable to treatment.
Laparoscopic repair of a perforated peptic ulcer is an amenable and feasible technique within the hands of experienced laparoscopic surgeon when the cases are early and properly diagnosed.
背景/目的:尽管抗溃疡药物和幽门螺杆菌根除广泛应用,穿孔性消化性溃疡(PPU)在 21 世纪仍频繁发生。本研究旨在验证腹腔镜治疗可改善其预后的假设。分析了与腹腔镜相关的并发症、死亡率和住院时间等治疗结果。
这是一项前瞻性描述性研究,于 2009 年 7 月至 2012 年 7 月进行。所有以急性腹痛就诊、临床诊断为穿孔性消化性溃疡的患者均纳入研究。本研究排除了溃疡合并出血和胃出口梗阻证据的患者,还排除了穿孔大于 10mm 的大穿孔和症状持续超过 36 小时的患者,因为担心发生感染性休克。
53 例 PPU 患者中,47 例被纳入研究,包括 41 例男性和 6 例女性,男女比例为 6.8:1。年龄 19-55 岁,平均年龄 39.5 ± 8.6 岁。45 例患者成功接受腹腔镜治疗,仅 2 例早期表现为低血容量休克的患者因严重出血转为剖腹手术。平均住院时间为 75 ± 12.6 小时。术后并发症包括 ICU 死亡 1 例,2 例行剖腹手术的患者术后发热,经治疗后均好转。
在有经验的腹腔镜外科医生手中,当病例早期且正确诊断时,腹腔镜修复穿孔性消化性溃疡是一种可行的方法。