Suppr超能文献

儿童肾移植中的差异、种族/民族和可及性。

Disparities, race/ethnicity and access to pediatric kidney transplantation.

机构信息

aDepartment of Pediatrics, The Children's Hospital of Philadelphia bDepartment of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA cDepartment of Surgery, Emory Transplant Center, Emory University dDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

出版信息

Curr Opin Nephrol Hypertens. 2013 May;22(3):336-43. doi: 10.1097/MNH.0b013e32835fe55b.

Abstract

PURPOSE OF REVIEW

Kidney transplantation remains the optimal treatment for children with end-stage renal disease; yet, in the United States, profound differences in access to transplant persist, with black children experiencing significantly reduced access to transplant compared with white children. The reasons for these disparities remain poorly understood. Several recent studies provide new insights into the interplay of socioeconomic status, racial/ethnic disparities and access to pediatric kidney transplantation.

RECENT FINDINGS

New evidence suggests that disparities are more pronounced in access to living vs. deceased donors. National allocation policies have mitigated racial differences in pediatric deceased donor kidney transplant (DDKT) access after waitlisting. However, disparities in access to DDKT are stark for minority emerging adults, who lose pediatric priority allocation. Although absence of health insurance poses an important barrier to transplant, even after adjustment for insurance status and neighborhood poverty, disparities persist. Differential access to care and unjust social structures are posited as important modifiable barriers to achieving equity in pediatric transplant access.

SUMMARY

Future approaches to overcome disparities in pediatric kidney transplant access must focus on the continuum of the transplant process, including equitable health care access. Public health advocacy efforts to promote national policies that address disparate multilevel socioeconomic factors are essential.

摘要

目的综述:肾移植仍然是治疗终末期肾病儿童的最佳方法;然而,在美国,儿童接受肾移植的机会存在显著差异,与白人儿童相比,黑人儿童接受肾移植的机会明显减少。造成这些差异的原因仍知之甚少。最近的几项研究为理解社会经济地位、种族/民族差异和儿童肾移植机会之间的相互作用提供了新的见解。

最近的发现:新的证据表明,在活体供体和已故供体之间,获得供体的机会差异更为明显。国家分配政策缓解了等待名单上的儿童已故供体肾移植(DDKT)获得的种族差异。然而,对于少数族裔的成年初显期患者来说,DDKT 的获得机会仍然存在明显的差异,他们失去了儿童优先分配的资格。尽管没有健康保险是移植的一个重要障碍,但即使在调整了保险状况和社区贫困状况后,差异仍然存在。护理机会的差异和不公正的社会结构被认为是实现儿童移植机会公平的重要可改变的障碍。

总结:未来克服儿童肾移植机会差异的方法必须侧重于移植过程的连续性,包括公平的医疗保健机会。公共卫生宣传工作对于促进解决不同层次社会经济因素的国家政策至关重要。

相似文献

1
Disparities, race/ethnicity and access to pediatric kidney transplantation.
Curr Opin Nephrol Hypertens. 2013 May;22(3):336-43. doi: 10.1097/MNH.0b013e32835fe55b.
2
Racial and ethnic differences in pediatric access to preemptive kidney transplantation in the United States.
Am J Transplant. 2013 Jul;13(7):1769-81. doi: 10.1111/ajt.12299. Epub 2013 Jun 3.
3
Racial disparities in pediatric access to kidney transplantation: does socioeconomic status play a role?
Am J Transplant. 2012 Feb;12(2):369-78. doi: 10.1111/j.1600-6143.2011.03888.x. Epub 2012 Jan 6.
5
Progress made toward equitable transplantation in children and young adults with kidney disease.
Pediatr Nephrol. 2024 Sep;39(9):2593-2600. doi: 10.1007/s00467-024-06309-5. Epub 2024 Feb 12.
6
Racial disparities in access to pediatric kidney transplantation since share 35.
J Am Soc Nephrol. 2012 Jun;23(6):1069-77. doi: 10.1681/ASN.2011121145. Epub 2012 Apr 26.
7
Racial and ethnic disparities in pediatric renal allograft survival in the United States.
Kidney Int. 2015 Mar;87(3):584-92. doi: 10.1038/ki.2014.345. Epub 2014 Oct 22.
8
Differences in access to kidney transplantation between Hispanic and non-Hispanic whites by geographic location in the United States.
Clin J Am Soc Nephrol. 2013 Dec;8(12):2149-57. doi: 10.2215/CJN.01560213. Epub 2013 Oct 10.
9
Racial disparities in preemptive referral for kidney transplantation in Georgia.
Clin Transplant. 2018 Sep;32(9):e13380. doi: 10.1111/ctr.13380. Epub 2018 Aug 26.
10
Disparities in Access to Timely Waitlisting Among Pediatric Kidney Transplant Candidates.
Pediatrics. 2024 Sep 1;154(3). doi: 10.1542/peds.2024-065934.

引用本文的文献

2
Neighborhood Socioeconomic Deprivation is Associated with Worse Outcomes in Pediatric Kidney Transplant Recipients.
Clin J Am Soc Nephrol. 2024 Oct 31;20(2):277-88. doi: 10.2215/CJN.0000000592.
3
Error Rates in Race and Ethnicity Designation Across Large Pediatric Health Systems.
JAMA Netw Open. 2024 Sep 3;7(9):e2431073. doi: 10.1001/jamanetworkopen.2024.31073.
4
Socioeconomic Position and Health Among Children and Adolescents With CKD Across the Life-Course.
Kidney Int Rep. 2024 Feb 1;9(5):1167-1182. doi: 10.1016/j.ekir.2024.01.042. eCollection 2024 May.
5
Predicting pediatric kidney transplant wait times: The unexplored landscape and pre-allocation transplant policies.
Pediatr Nephrol. 2024 Aug;39(8):2275-2278. doi: 10.1007/s00467-024-06308-6. Epub 2024 Feb 2.
6
Predicting wait time for pediatric kidney transplant: a novel index.
Pediatr Nephrol. 2024 Aug;39(8):2483-2493. doi: 10.1007/s00467-023-06232-1. Epub 2024 Jan 12.
7
Promoting Equity In Clinical Decision Making: Dismantling Race-Based Medicine.
Health Aff (Millwood). 2023 Oct;42(10):1369-1373. doi: 10.1377/hlthaff.2023.00545.
8
Discrepancies in Race and Ethnicity in the Electronic Health Record Compared to Self-report.
J Racial Ethn Health Disparities. 2023 Dec;10(6):2670-2675. doi: 10.1007/s40615-022-01445-w. Epub 2022 Nov 23.
9
Transplant access for children: there is more to be done.
Pediatr Nephrol. 2023 Apr;38(4):941-944. doi: 10.1007/s00467-022-05787-9. Epub 2022 Nov 12.

本文引用的文献

1
Does expanding public insurance prevent material hardship for families with children?
Med Care Res Rev. 2013 Jun;70(3):267-86. doi: 10.1177/1077558712470566. Epub 2013 Jan 6.
2
Access to patient-centered medical home among Ohio's Children with Special Health Care Needs.
J Child Health Care. 2013 Jun;17(2):186-96. doi: 10.1177/1367493512456111. Epub 2012 Dec 12.
5
The health policy election.
JAMA. 2012 Oct 24;308(16):1633-4. doi: 10.1001/jama.2012.13667.
6
An examination of racial/ethnic disparities in children's oral health in the United States.
J Public Health Dent. 2013 Spring;73(2):166-74. doi: 10.1111/j.1752-7325.2012.00367.x. Epub 2012 Sep 13.
8
Impact of navigators on completion of steps in the kidney transplant process: a randomized, controlled trial.
Clin J Am Soc Nephrol. 2012 Oct;7(10):1639-45. doi: 10.2215/CJN.11731111. Epub 2012 Jul 12.
9
Influence of race, ethnicity and socioeconomic status on kidney disease.
Nat Rev Nephrol. 2012 Sep;8(9):533-41. doi: 10.1038/nrneph.2012.117. Epub 2012 Jun 26.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验