Tabaee Abtin, Kamat Ameet, Shrivastava Raj
Department of Otolaryngology, Head and Neck Surgery, Beth Israel Medical Center, New York, New York 10003, USA.
J Neurol Surg A Cent Eur Neurosurg. 2013 Sep;74(5):313-7. doi: 10.1055/s-0032-1333129. Epub 2013 Mar 26.
Skull base reconstruction in the setting of revision endoscopic pituitary surgery with intraoperative cerebrospinal fluid (CSF) leak represents a unique challenge.
The demographics and outcomes of four patients undergoing revision endoscopic pituitary surgery with high-volume intraoperative CSF leak are described. The "gasket-seal" technique of sellar repair using bioabsorbable mini-plate is described.
The indications for surgery were macroadenoma with suprasellar extension and optic nerve compression in three patients and growth hormone-secreting tumor in one patient with acromegaly. The multilayered reconstruction consisted of autologous fat placed in the tumor cavity followed by reconstruction of the sellar floor with an oversized sheet of either fascia lata or acellular dermal matrix placed over the skull base defect and sunken into the sella with a bioabsorbable mini-plate. One patient experienced postoperative CSF leak on postoperative day 2 that resolved with lumbar drainage alone. All patients were noted to have a well mucosalized sphenoid sinus and were free of CSF leak at last follow-up.
Sellar reconstruction following endoscopic pituitary surgery represents a technical challenge, especially in revision cases with high-volume intraoperative CSF leak. The early experience with the "gasket-seal" closure using the bioabsorbable mini-plate appears favorable. Lumbar drain may be indicated in patients with postoperative CSF leak.
在内镜下垂体瘤翻修手术中,若术中出现脑脊液漏,颅底重建是一项独特的挑战。
描述了4例术中出现大量脑脊液漏的内镜下垂体瘤翻修手术患者的人口统计学资料和手术结果。介绍了使用可生物吸收微型钢板进行鞍底修复的“垫片密封”技术。
3例患者的手术指征为巨大腺瘤伴鞍上延伸及视神经受压,1例肢端肥大症患者的手术指征为生长激素分泌型肿瘤。多层重建包括在肿瘤腔内放置自体脂肪,然后用一块超大的阔筋膜或脱细胞真皮基质覆盖颅底缺损并下沉至鞍内,再用可生物吸收微型钢板重建鞍底。1例患者在术后第2天出现脑脊液漏,仅通过腰椎引流就得以解决。所有患者蝶窦黏膜化良好,在最后一次随访时均无脑脊液漏。
内镜下垂体瘤手术后的鞍底重建是一项技术挑战,尤其是在术中出现大量脑脊液漏的翻修病例中。使用可生物吸收微型钢板进行“垫片密封”闭合的早期经验似乎良好。术后出现脑脊液漏的患者可能需要进行腰椎引流。