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抑郁对脊髓损伤后身体并发症的影响:行为机制和医疗保健意义。

The influence of depression on physical complications in spinal cord injury: behavioral mechanisms and health-care implications.

机构信息

UBC School of Population and Public Health, The Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Spinal Cord. 2013 Apr;51(4):260-6. doi: 10.1038/sc.2013.3. Epub 2013 Feb 18.

Abstract

STUDY DESIGN

This study is a literature review and a proposed conceptual model.

OBJECTIVES

The objective of this study is to develop a conceptual model to explore the relationship between the presence of depressive symptoms and secondary physical complications such as pressure ulcers, urinary tract infections and autonomic dysreflexia in spinal cord injury (SCI).

SETTING

Community setting for individuals with SCI.

METHODS

A conceptual model explaining the mechanism underlying the relationship between depression and secondary physical SCI complications was developed based on the International Classification of Functioning, Disability and Health (ICF). A literature review was conducted to develop the model and to identify potential mechanisms responsible for the association.

RESULTS

A conceptual model based on ICF was created, informed by the literature discussing the link between depression and secondary physical SCI complications. Evidence in the literature was located that supports both a causal connection between depression and increased physical complications and/or the potential mechanisms mediating that connection.

CONCLUSION

The proposed model can be utilized to encourage further research on the influence of depression on SCI outcomes and the importance of prompt and effective identification and treatment of depressive symptoms. Additional research is needed to assess the relationship between depression and secondary physical SCI complications, and to test the validity of the model.

摘要

研究设计

本研究为文献回顾和概念模型构建。

研究目的

本研究旨在构建一个概念模型,以探索抑郁症状与脊髓损伤(SCI)继发的躯体并发症(如压疮、尿路感染和自主神经反射异常)之间的关系。

研究场所

SCI 患者的社区环境。

研究方法

根据国际功能、残疾和健康分类(ICF)构建一个解释抑郁与继发躯体 SCI 并发症之间关系机制的概念模型。通过文献回顾来构建模型并确定可能的关联机制。

研究结果

基于 ICF 的概念模型得以建立,该模型源于讨论抑郁与继发躯体 SCI 并发症之间联系的文献。文献中发现的证据支持抑郁与躯体并发症增加之间存在因果关系,以及潜在的中介机制。

结论

所提出的模型可用于鼓励进一步研究抑郁对 SCI 结局的影响,以及及时识别和有效治疗抑郁症状的重要性。需要进一步研究来评估抑郁与继发躯体 SCI 并发症之间的关系,并检验该模型的有效性。

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