School of Chemical Engineering and Advanced Materials, Newcastle University, United Kingdom.
Environ Pollut. 2013 Jul;178:498-502. doi: 10.1016/j.envpol.2013.03.010. Epub 2013 Apr 2.
Silver nanoparticles (AgNPS) are an important model system for studying potential environmental risks posed by the use of nanomaterials. So far there is no consensus as to whether toxicity is due to AgNPs themselves or Ag(+) ions leaching from their surfaces. In sea urchin Paracentrotus lividus, AgNPs cause dose dependent developmental defects such as delayed development, bodily asymmetry and shortened or irregular arms, as well as behavioural changes, particularly in swimming patterns, at concentration ∼0.3 mg/L AgNPs. It has been observed that AgNPs are more toxic than their equivalent Ag(+) ion dose.
银纳米粒子(AgNPS)是研究纳米材料使用带来的潜在环境风险的重要模型系统。目前,对于毒性是由于 AgNPs 本身还是其表面浸出的 Ag(+) 离子导致,尚无共识。在海胆 Paracentrotus lividus 中,AgNPs 在浓度约为 0.3mg/L 的情况下,会导致剂量依赖性的发育缺陷,如发育迟缓、身体不对称以及臂部长短不一或不规则,以及行为改变,特别是游泳模式。已经观察到 AgNPs 比其等效的 Ag(+)离子剂量更具毒性。