Hu Ming-Gen, Zhao Guo-Dong, Ouyang Cai-Guo, Xu Da-Bin, Liu Rong
Department of Surgical Oncology, The General Hospital of Chinese People’s Liberation Army, Beijing, China.
J Laparoendosc Adv Surg Tech A. 2013 Apr;23(4):332-8. doi: 10.1089/lap.2012.0397.
Laparoscopic hepatectomy is widely used in the surgical treatment of left-sided hepatolithiasis (LSH). Lithotomy using a cholangioscope usually is required for the treatment of concurrent right-sided hepatolithiasis or choledocholithiasis. The primary objective of this study was to evaluate the effectiveness and safety of gallstone elimination using cholangioscopy through the left hepatic duct (LHD) orifice versus the common bile duct (CBD).
Eligible LSH patients (n=41) were scheduled for laparoscopic left lateral segmentectomy or left hemihepatectomy with intraoperative biliary exploration using cholangioscopy through the LHD orifice (LHD group, n=23) or the CBD (CBD group, n=18) at the discretion of patients. Laparoscopic T-tube insertion was performed in selected patients. Patients were regularly followed up at monthly intervals or more frequently in the presence of any symptom. The primary outcome measures included overall operative time, duration of the cholangioscopy procedure, volume of blood loss, length of hospital stay, and frequency of procedure-related complications.
The two groups were comparable in sex, age, symptoms, site of lesion, and gallstone comorbidities (P>.05). Of the 18 patients in the CBD group, 12 (66.7%) patients had a T-tube inserted in contrast to 1 (4.5%) patient in the LHD group. The two groups were comparable in cholangioscopy duration and volume of blood loss (P>.05), whereas the LHD group had a significantly shorter operative time than the CBD group (221.4 ± 58.6 minutes versus 171.2 ± 63.5 minutes; P<.05). The postoperative duration of hospitalization was significantly shorter in the LHD group than in the CBD group (7.5 ± 2.2 days versus 4.2 ± 1.9 days; P<.05). No patient showed any recurrence of gallstones or cholangitis during the follow-up period.
As an effective and safe technique that is comparable to choledochotomy, LHD cholangioscopy is a preferred alternative to choledochotomy in the laparoscopic treatment of LSH because it offers patients shorter operative duration and length of hospitalization.
腹腔镜肝切除术广泛应用于左侧肝内胆管结石(LSH)的外科治疗。对于合并右侧肝内胆管结石或胆总管结石的治疗,通常需要使用胆道镜取石。本研究的主要目的是评估经左肝管(LHD)开口与经胆总管(CBD)使用胆道镜清除结石的有效性和安全性。
符合条件的LSH患者(n = 41)计划接受腹腔镜左外侧段切除术或左半肝切除术,术中根据患者意愿经LHD开口(LHD组,n = 23)或CBD(CBD组,n = 18)使用胆道镜进行胆道探查。部分患者进行了腹腔镜T管置入。患者每月定期随访,出现任何症状时随访更频繁。主要观察指标包括总手术时间、胆道镜检查时间、失血量、住院时间以及与手术相关并发症的发生率。
两组在性别、年龄、症状、病变部位和结石合并症方面具有可比性(P >.05)。CBD组的18例患者中,12例(66.7%)置入了T管,而LHD组只有1例(4.5%)患者置入了T管。两组在胆道镜检查时间和失血量方面具有可比性(P >.05),而LHD组的手术时间明显短于CBD组(221.4 ± 58.6分钟对171.2 ± 63.5分钟;P <.05)。LHD组术后住院时间明显短于CBD组(7.5 ± 2.2天对4.2 ± 1.9天;P <.05)。随访期间没有患者出现结石复发或胆管炎。
作为一种与胆总管切开术效果相当的有效且安全的技术,LHD胆道镜检查在腹腔镜治疗LSH中是胆总管切开术的首选替代方法,因为它为患者提供了更短的手术时间和住院时间。