Karolinska Institutet, Department of Dental Medicine, Division of Periodontology , Huddinge , Sweden.
Acta Odontol Scand. 2013 Nov;71(6):1625-31. doi: 10.3109/00016357.2013.788207. Epub 2013 Apr 16.
The aim of this study was to evaluate the difference between subjects with pre-diabetes, well or poorly controlled diabetes mellitus type 2 (T2D) and non-diabetes concerning such medical risk factors as hemoglobin A1c, body mass index (BMI) and waist circumference (WC) with periodontal conditions.
BMI, WC, PI, BOP, PD and marginal bone level (MBL) were recorded. Hemoglobin A1c (HbA1c) level and random blood glucose level (RBGL) were analyzed.
Forty-five subjects were pre-diabetics, 64 subjects had poorly controlled T2D, 28 subjects had well controlled T2D and 76 subjects were non-diabetics. Non-diabetics, pre-diabetics as well as subjects with T2D were overweight. Females in all groups had increased mean levels of WC. Number of PD ≥ 6 mm were increased in subjects with poorly controlled T2D compared to non-diabetics and pre-diabetics (p < 0.05).
Pre-diabetic subjects showed the same periodontal conditions as non-diabetic subjects. Forty-five of the subjects reporting to have no diabetes were pre-diabetics. Non-diabetic, pre-diabetic and diabetic subjects were overweight. Subjects with poorly controlled T2D had severe periodontal conditions.
本研究旨在评估患有糖尿病前期、血糖控制良好或较差的 2 型糖尿病(T2D)患者与非糖尿病患者之间的差异,这些差异与糖化血红蛋白、体重指数(BMI)和腰围(WC)等医学危险因素以及牙周状况有关。
记录 BMI、WC、PI、BOP、PD 和边缘骨水平(MBL)。分析糖化血红蛋白(HbA1c)水平和随机血糖水平(RBGL)。
45 名受试者为糖尿病前期,64 名受试者为血糖控制不佳的 T2D,28 名受试者为血糖控制良好的 T2D,76 名受试者为非糖尿病患者。非糖尿病患者、糖尿病前期患者以及 T2D 患者均超重。所有组别的女性 WC 均值均增加。与非糖尿病患者和糖尿病前期患者相比,血糖控制不佳的 T2D 患者 PD≥6mm 的数量增加(p<0.05)。
糖尿病前期患者的牙周状况与非糖尿病患者相同。报告无糖尿病的 45 名患者为糖尿病前期患者。非糖尿病患者、糖尿病前期患者和糖尿病患者超重。血糖控制不佳的 T2D 患者牙周状况严重。