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超声引导腹横肌平面(TAP)阻滞用于腹腔镜胃旁路手术:一项前瞻性随机对照双盲试验。

Ultrasound-guided transversus abdominis plane (TAP) block for laparoscopic gastric-bypass surgery: a prospective randomized controlled double-blinded trial.

机构信息

Department of Anesthesia and Pain Management, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada.

出版信息

Obes Surg. 2013 Aug;23(8):1309-14. doi: 10.1007/s11695-013-0958-3.

Abstract

BACKGROUND

Despite the laparoscopic approach, patients can suffer moderate to severe pain following bariatric surgery. This randomized controlled double-blinded trial investigated the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) blocks for laparoscopic gastric-bypass surgery.

METHODS

Seventy patients undergoing laparoscopic gastric-bypass surgery were randomized to receive either bilateral ultrasound-guided subcostal TAP block injections after induction of general anesthesia or none. All patients received trocar insertion site local anesthetic infiltration and systemic analgesia. The primary outcome was cumulative opioid consumption (IV morphine equivalent) during the first 24 h postoperatively. Interval opioid consumption, pain severity scores, rates of nausea or vomiting, and rates of pruritus were measured during phase I recovery, and at 24 and 48 h postoperatively.

RESULTS

There was no difference in cumulative opioid consumption during the first 24 h postoperatively between the TAP (32.2 mg [95% CI, 27.6-36.7]) and control (35.6 mg [95% CI, 28.6-42.5]; P = 0.41) groups. Postoperative opioid consumptions during phase I recovery and the 24-48-h interval were similar between groups, as were pain scores at rest and with movement during all measured intervals. The rates of nausea or vomiting and pruritus were equivalent.

CONCLUSIONS

Bilateral TAP blocks do not provide additional analgesic benefit when added to trocar insertion site local anesthetic infiltration and systemic analgesia for laparoscopic gastric-bypass surgery.

摘要

背景

尽管采用了腹腔镜方法,但患者在接受减肥手术后仍可能遭受中度至重度疼痛。本随机对照双盲试验研究了超声引导腹横肌平面(TAP)阻滞对腹腔镜胃旁路手术的镇痛效果。

方法

70 例行腹腔镜胃旁路手术的患者随机分为两组,一组在全身麻醉诱导后接受双侧超声引导肋缘下 TAP 阻滞注射,另一组不接受阻滞。所有患者均接受了套管插入部位局部麻醉浸润和全身镇痛。主要结局是术后 24 小时内累积阿片类药物(静脉注射吗啡等效物)的消耗量。在第一阶段恢复期间以及术后 24 小时和 48 小时测量了间隔性阿片类药物消耗、疼痛严重程度评分、恶心或呕吐发生率和瘙痒发生率。

结果

在术后 24 小时内,TAP 组(32.2mg [95%CI,27.6-36.7])和对照组(35.6mg [95%CI,28.6-42.5])之间的累积阿片类药物消耗无差异(P=0.41)。在第一阶段恢复和 24-48 小时间隔期间,两组之间的术后阿片类药物消耗相似,在所有测量间隔期间,静息和运动时的疼痛评分也相似。恶心或呕吐和瘙痒的发生率相当。

结论

在腹腔镜胃旁路手术中,与套管插入部位局部麻醉浸润和全身镇痛联合应用时,双侧 TAP 阻滞并不能提供额外的镇痛益处。

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