Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta GA 30333, United States.
Vaccine. 2013 May 31;31(24):2673-9. doi: 10.1016/j.vaccine.2013.04.009. Epub 2013 Apr 16.
Healthcare provider (HCP) reporting to the Vaccine Adverse Event Reporting System (VAERS) is important to assuring the safety of U.S. licensed vaccines. HCP awareness of and practices regarding reporting of adverse events following immunization (AEFI) is understudied.
A large, nationally representative sample of U.S. office-based HCP across three occupational groups (physicians, mid-level providers [physician assistants, advanced practice nurses] and nurses) and three primary care practice areas (pediatrics, family medicine, internal medicine) were surveyed utilizing standardized methodology. We assessed HCP familiarity with VAERS, the situations under which they were likely to report an AEFI, and the methods they used and preferred for reporting. We used logistic regression to determine factors associated with HCP not reporting AEFI to VAERS.
Our survey response rate was 54.9%. The percentage of HCP aware of VAERS (71%) varied by occupation and primary care practice area. About 37% of HCP had identified at least one AEFI with only 17% of these indicating that they had ever reported to VAERS. More serious events were more likely to be reported. Factors associated with HCP not reporting AEFI included: HCP not familiar versus very familiar with filing a paper VAERS report (OR=12.84; p<0.0001), primary care practice area of internal medicine versus pediatrics (OR=4.22; p=0.0005), and HCP not familiar versus very familiar with when it was required to file a VAERS report (OR=5.52; p=0.0013).
Specific educational interventions targeted to HCP likely to see AEFI but not currently reporting may improve vaccine safety reporting practices.
向疫苗不良事件报告系统（VAERS）报告医疗保健提供者（HCP）对于确保美国许可疫苗的安全性非常重要。HCP 对疫苗接种后不良反应（AEFI）报告的认识和实践仍在研究之中。
利用标准化方法，对三个职业群体（医生、中级提供者[医生助理、高级执业护士]和护士）和三个初级保健实践领域（儿科、家庭医学、内科）的美国办公室为基础的 HCP 进行了一项大型、全国代表性样本调查。我们评估了 HCP 对 VAERS 的熟悉程度、他们可能报告 AEFI 的情况，以及他们使用和偏好的报告方法。我们使用逻辑回归来确定与 HCP 未向 VAERS 报告 AEFI 相关的因素。
我们的调查回复率为 54.9%。对 VAERS 有一定了解的 HCP 比例（71%）因职业和初级保健实践领域而异。约 37%的 HCP 已经确定了至少一种 AEFI，但只有 17%的 HCP 表示他们曾经向 VAERS 报告过。更严重的事件更有可能被报告。与 HCP 未报告 AEFI 相关的因素包括：HCP 对填写纸质 VAERS 报告不熟悉与非常熟悉（OR=12.84；p<0.0001）、内科与儿科的初级保健实践领域（OR=4.22；p=0.0005）以及 HCP 对何时需要提交 VAERS 报告不熟悉与非常熟悉（OR=5.52；p=0.0013）。
针对那些可能看到 AEFI 但目前未报告的 HCP，进行有针对性的特定教育干预措施可能会改善疫苗安全性报告实践。
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