Morimoto K, Matsuzaki M, Tohma Y, Ono S, Tanaka N, Michishige H, Murata K, Anno Y, Kusukawa R
Department of Internal Medicine, Yamaguchi University School of Medicine, Ube, Japan.
Am J Cardiol. 1990 Jul 1;66(1):85-91. doi: 10.1016/0002-9149(90)90741-i.
Transesophageal echocardiography (horizontal sector scan) was performed in 11 patients with secundum atrial septal defect (ASD). In all 11 patients, transesophageal echocardiography presented the definite visualization of the defect and a clear laminar shunt flow that showed its 2 peaks in late systole and late diastole. We estimated the size of ASD and a shunt volume across the defect by using transesophageal echocardiography. The defect size determined by transesophageal echocardiography was correlated with the surgical measurement (horizontal width, r = 0.92, p less than 0.001; vertical length, r = 0.85, p less than 0.01). A significant high correlation was shown between the shunt volume measured by transesophageal echocardiography and that by Fick's method (r = 0.87, p less than 0.01). There was no significant correlation between the pulmonary to systemic flow volume (ratio) and the mean shunt flow velocity across ASD, although a high linear correlation was observed between the pulmonary to systemic flow ratio and the defect size in horizontal direction (r = 0.82, p less than 0.01). Transesophageal echocardiography used for diagnosis and quantitative evaluation of ASD could be performed easily and satisfactorily within 10 minutes. Thus, transesophageal echocardiography is a useful method in evaluation of the defect size and the shunt flow volume of ASD. The mean shunt flow velocity was not a reliable index for estimating the shunt flow volume. The defect size might be a valuable determinant of left-to-right shunt volume in ASD.
对11例继发孔型房间隔缺损(ASD)患者进行了经食管超声心动图检查(水平扇形扫描)。在所有11例患者中,经食管超声心动图均清晰显示了缺损及明确的层流分流,该分流在收缩期末期和舒张期末期出现两个峰值。我们通过经食管超声心动图评估了ASD的大小及缺损处的分流血量。经食管超声心动图测定的缺损大小与手术测量值相关(水平宽度,r = 0.92,p < 0.001;垂直长度,r = 0.85,p < 0.01)。经食管超声心动图测量的分流血量与Fick法测量的分流血量之间显示出显著的高度相关性(r = 0.87,p < 0.01)。尽管观察到肺循环与体循环血流量之比(分流比)与ASD水平方向的缺损大小之间呈高度线性相关(r = 0.82,p < 0.01),但肺循环与体循环血流量之比(分流比)与ASD平均分流流速之间无显著相关性。用于ASD诊断和定量评估的经食管超声心动图检查可在10分钟内轻松且满意地完成。因此,经食管超声心动图是评估ASD缺损大小和分流血量的一种有用方法。平均分流流速不是估计分流血量的可靠指标。缺损大小可能是ASD左向右分流血量的一个重要决定因素。