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中国西部农村 36 个月以下儿童贫血严重程度。

Severity of anemia among children under 36 months old in rural western China.

机构信息

Department of Epidemiology and Health Statistics, School of Public Health, College of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.

出版信息

PLoS One. 2013 Apr 23;8(4):e62883. doi: 10.1371/journal.pone.0062883. Print 2013.

Abstract

OBJECTIVE

To describe severity of anemia and explore its determinants among children under 36 months old in rural western China.

STUDY DESIGN

The family information of 6711 children was collected and their hemoglobin was measured in 2005. A generalized estimated equation (GEE) linear model was used to identify the determinants of severity of childhood anemia.

RESULTS

The prevalence of mild, moderate and severe anemia among these children was 27.4%, 21.9% and 3.2% respectively. GEE model analysis showed that province-level region and severity of maternal anemia affected the severity of childhood anemia not only in 0-5 months but also beyond 5 months. In addition, children aged 0-5 months in families using iron pot (coefficient = -0.26 95%CI -0.41,-0.12) had seldom more severe anemia, and children aged 6-36 months in families more than 4 members (coefficient = -0.03 95%CI -0.06,-0.01) or of Han ethnicity (coefficient = -0.08 95%CI -0.13,-0.04) seldom had more severe anemia but boys (coefficient = 0.03 95%CI 0.01,0.06) or younger children (6-11 month vs 30-36 month: coefficient = 0.23 95%CI 0.17, 0.28; 12-17 month vs 30-36 month: coefficient = 0.19 95%CI 0.15,0.24; 18-23 vs 30-36 month: coefficient = 0.09 95%CI 0.04,0.13) had more severe anemia.

CONCLUSION

The prevalence of moderate-to-severe anemia in these children was about 25%. Province-level region, iron pot use, family size, ethnicity, age and gender of children and severity of maternal anemia were important determinants of the severity of childhood anemia. These findings have some important implications for health policy decision for childhood anemia in rural western China.

摘要

目的

描述中国西部农村地区 36 个月以下儿童贫血的严重程度,并探讨其决定因素。

研究设计

2005 年收集了 6711 名儿童的家庭信息,并测量了他们的血红蛋白。采用广义估计方程(GEE)线性模型来确定儿童贫血严重程度的决定因素。

结果

这些儿童中轻度、中度和重度贫血的患病率分别为 27.4%、21.9%和 3.2%。GEE 模型分析表明,省级地区和母亲贫血的严重程度不仅影响 0-5 个月儿童的贫血严重程度,也影响 5 个月以上儿童的贫血严重程度。此外,0-5 个月时家中使用铁锅的儿童(系数=-0.26,95%CI-0.41,-0.12)较少出现严重贫血,6-36 个月时家中人口数多于 4 人的儿童(系数=-0.03,95%CI-0.06,-0.01)或汉族(系数=-0.08,95%CI-0.13,-0.04)的儿童也较少出现严重贫血,但男孩(系数=0.03,95%CI0.01,0.06)或年龄较小的儿童(6-11 个月 vs. 30-36 个月:系数=0.23,95%CI0.17,0.28;12-17 个月 vs. 30-36 个月:系数=0.19,95%CI0.15,0.24;18-23 个月 vs. 30-36 个月:系数=0.09,95%CI0.04,0.13)更易出现严重贫血。

结论

这些儿童中中重度贫血的患病率约为 25%。省级地区、铁锅使用、家庭规模、民族、儿童年龄和性别以及母亲贫血的严重程度是儿童贫血严重程度的重要决定因素。这些发现对中国西部农村地区儿童贫血的卫生政策决策具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e5/3633837/2b752bd04de0/pone.0062883.g001.jpg

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