Faculty of Rehabilitation Sciences, The University of Jordan, Amman, Jordan.
Int J Med Sci. 2013 Apr 25;10(6):790-5. doi: 10.7150/ijms.5140. Print 2013.
Different clinical profiles of knee osteoarthritis (KOA) have been reported in the literature. The aim of this investigation was to describe the clinical patterns of KOA in an ethnically distinct and homogenous population that has not been widely reported. Patients with KOA were seen in outpatient rehabilitation and orthopedic clinic of Jordan University Hospital (JUH), to determine any possible association between age, BMI, radiographic severity, and pain severity.
Patients diagnosed with KOA attending an outpatient rehabilitation clinic at JUH were studied to describe their clinical characteristics. They were included based on criteria developed by the American College of Rheumatology. Detailed histories, clinical examinations and X-rays, and anthropometric data were obtained. Data analysis focused on descriptive statistics and correlations among demographic and clinical characteristics.
The study included 214 patients with a mean age of 55.3 years (range = 30-84 years). The mean BMI was 29.5± 5.6. We found a significant moderate positive correlation between age and radiographic severity of KOA (0.435; p <. 001) and pain severity (0.383; p. <. 001). There was also a significant weak positive correlation between BMI, radiographic severity of KOA (0.242, p <. 05), and pain severity (0.266, p. <. 01).
We concluded that in this hospital-based cohort study in Jordan, the clinical pattern of KOA is comparable to Western cultures. However, the combination of BMI and mechanical loading during everyday activities that include different religious and cultural habits and may help explain the high level of radiographic severity in our sample.
膝关节骨关节炎(KOA)的不同临床特征在文献中有报道。本研究旨在描述在一个尚未广泛报道的具有独特民族和同质人群中 KOA 的临床模式。在约旦大学医院(JUH)的门诊康复和骨科诊所中,对 KOA 患者进行了检查,以确定年龄、BMI、影像学严重程度和疼痛严重程度之间是否存在任何可能的关联。
在 JUH 门诊康复诊所就诊的被诊断为 KOA 的患者被纳入本研究,以描述其临床特征。他们是根据美国风湿病学会制定的标准纳入的。详细的病史、临床检查和 X 射线以及人体测量数据均被获取。数据分析集中于描述性统计和人口统计学及临床特征之间的相关性。
本研究共纳入 214 例患者,平均年龄为 55.3 岁(范围 30-84 岁)。平均 BMI 为 29.5±5.6。我们发现年龄与 KOA 的影像学严重程度(0.435;p<.001)和疼痛严重程度(0.383;p<.001)之间存在显著的中度正相关。BMI 与 KOA 的影像学严重程度(0.242,p<.05)和疼痛严重程度(0.266,p<.01)之间也存在显著的弱正相关。
我们得出结论,在这项基于医院的约旦队列研究中,KOA 的临床模式与西方文化相似。然而,BMI 与日常活动中的机械负荷的结合,包括不同的宗教和文化习惯,可能有助于解释我们样本中影像学严重程度较高的原因。