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老年期抑郁症认知行为治疗的治疗反应的心理社会预测因素:一项探索性研究。

Psychosocial predictors of treatment response to cognitive-behavior therapy for late-life depression: an exploratory study.

机构信息

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.

出版信息

Aging Ment Health. 2013;17(7):830-8. doi: 10.1080/13607863.2013.791661. Epub 2013 Apr 30.

Abstract

OBJECTIVE

The primary objective of this study was to examine a variety of potential predictors of response to Cognitive Behavioral Therapy (CBT) in depressed older adults.

METHOD

Sixty older adults with a clinical diagnosis of major or minor depression or dysthymic disorder received 12 individual sessions of CBT over a three- to four-month-period. The BDI-II was administered pre- and post-intervention to assess change in the level of depression. A cutoff score of 13 or less at post was used to determine positive treatment response. A variety of measures (obtained at baseline) were evaluated using hierarchical regression techniques to predict improvement following treatment.

RESULTS

Individuals who showed greater improvement were: (a) more open to new experiences; (b) less negatively affected by past stressors; (c) less inclined to have an external locus of control but more likely to cite others as responsible for negative stress in their lives; and (d) were more likely to seek emotional support when symptomatic. Lower education level and reported use of active coping strategies at baseline were associated with less improvement. Other variables (e.g., age, overall physical health, and cognitive status) were not associated with treatment response. Use of logistic regression to predict responders vs. nonresponders yielded a similar pattern.

CONCLUSION

These findings agree with prior research confirming the effectiveness of a brief CBT intervention for older depressed persons and suggest further exploration of several psychosocial factors that may contribute to a stronger response to CBT.

摘要

目的

本研究的主要目的是探讨各种可能预测接受认知行为疗法(CBT)的老年抑郁症患者反应的预测因素。

方法

60 名患有临床诊断为重度或轻度抑郁症或心境恶劣障碍的老年人在三至四个月的时间内接受了 12 次个体 CBT 治疗。在干预前后使用 BDI-II 评估抑郁程度的变化。采用 BDI-II 的后测得分 13 分或以下来确定治疗的积极反应。使用分层回归技术评估各种措施(在基线时获得),以预测治疗后的改善情况。

结果

显示出更大改善的个体是:(a)对新体验更开放;(b)过去的压力源对他们的负面影响较小;(c)不太倾向于具有外部控制点,但更有可能将他人视为生活中负面压力的责任人;(d)在有症状时更倾向于寻求情感支持。较低的教育水平和基线时报告的积极应对策略的使用与改善程度较低有关。其他变量(例如年龄、总体身体健康状况和认知状况)与治疗反应无关。使用逻辑回归预测反应者与非反应者得出了类似的模式。

结论

这些发现与先前的研究一致,证实了简短的 CBT 干预对老年抑郁患者的有效性,并进一步探讨了一些可能对 CBT 反应更强的心理社会因素。

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