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高效抗逆转录病毒治疗时代艾滋病毒/艾滋病感染者健康相关生活质量的性别差异

Gender Differences in Health Related Quality of Life of People Living with HIV/AIDS in the Era of Highly Active Antiretroviral Therapy.

作者信息

Vigneshwaran Easwaran, Padmanabhareddy Yiragam, Devanna Nayakanti, Alvarez-Uria Gerardo

机构信息

Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical Education and Research, Anantapur, India.

出版信息

N Am J Med Sci. 2013 Feb;5(2):102-7. doi: 10.4103/1947-2714.107526.

Abstract

BACKGROUND

Data about the health-related quality of life (HR-QOL) of people living with HIV/AIDS (PLHA) after the implementation of free antiretroviral treatment in India are scarce.

AIM

The study was to describe the HR-QOL and gender differences of PLHA in rural India.

MATERIALS AND METHODS

Cross sectional study of 120 PLHA who came to the outpatient department in a rural district hospital. Assessment of the HR-QOL was performed through interviews using a validated structured questionnaire from the Medical Outcome Study HIV Health Survey. Linear regression with robust standard errors was used for multivariable analysis.

RESULTS

Domains related to social and daily activities such as cognitive, role and social functioning had lower HR-QOL scores than domains related to physical health. Men had higher scores of HR-QOL in health transition, perceived HR-QOL, health distress, social functioning and role functioning. In multivariable analysis, factors associated with poorer HR-QOL were female sex, lower levels of education and being widowed or separated in women.

CONCLUSIONS

HR-QOL of PLHA in rural India is poor, especially in widowed or separated women and people with lower levels of education. There is an urgent need of implementing programmes for improving the HR-QOL of HIV infected women in rural India.

摘要

背景

在印度实施免费抗逆转录病毒治疗后,关于艾滋病毒/艾滋病感染者(PLHA)健康相关生活质量(HR-QOL)的数据很少。

目的

本研究旨在描述印度农村地区PLHA的HR-QOL及性别差异。

材料与方法

对一家农村地区医院门诊的120名PLHA进行横断面研究。使用来自医疗结果研究艾滋病毒健康调查的经过验证的结构化问卷,通过访谈对HR-QOL进行评估。多变量分析采用具有稳健标准误差的线性回归。

结果

与社会和日常活动相关的领域,如认知、角色和社会功能,其HR-QOL得分低于与身体健康相关的领域。男性在健康转变、感知的HR-QOL、健康困扰、社会功能和角色功能方面的HR-QOL得分较高。在多变量分析中,与较差HR-QOL相关的因素包括女性、教育水平较低以及女性丧偶或分居。

结论

印度农村地区PLHA的HR-QOL较差,尤其是丧偶或分居的女性以及教育水平较低的人群。迫切需要实施相关项目来改善印度农村地区艾滋病毒感染女性的HR-QOL。

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