Jávor T
Acta Physiol Acad Sci Hung. 1976;47(4):317-22.
The author made a review about the origin, the biochemistry the physiological and pathological roles of gastrointestinal peptide hormones. They originate from the APUD cell system, chemically from the ancient growth hormone, or placental lactogen. The theoretical prosecgastrin's first sequencies form the "secretin family", the tail sequencies form the "gastrin family". The author describes many details of their effects on the different gastrointestinal organs, they behave mainly antagonistic way to each other. Finally a discussions is given about their role in the development of peptic ulcer, in the WDHA syndrome and in malabsorption.
作者对胃肠肽激素的起源、生物化学、生理和病理作用进行了综述。它们起源于APUD细胞系统，化学结构源于古老的生长激素或胎盘催乳素。理论上，前胃泌素的首个序列构成“促胰液素家族”，尾部序列构成“胃泌素家族”。作者描述了它们对不同胃肠器官作用的许多细节，它们之间主要表现为相互拮抗。最后讨论了它们在消化性溃疡、WDHA综合征和吸收不良发展中的作用。
