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跟腱断裂手术与保守治疗早期负重后的再断裂率:一项荟萃分析

Rerupture rate after early weightbearing in operative versus conservative treatment of Achilles tendon ruptures: a meta-analysis.

作者信息

van der Eng Dorien M, Schepers Tim, Goslings J Carel, Schep Niels W L

机构信息

Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.

出版信息

J Foot Ankle Surg. 2013 Sep-Oct;52(5):622-8. doi: 10.1053/j.jfas.2013.03.027. Epub 2013 May 7.

Abstract

Whether Achilles tendon rupture benefits from surgery or conservative treatment remains controversial. Moreover, the outcome can be influenced by the rehabilitation protocol. The goal of the present meta-analysis was to compare the rerupture rate after surgical repair of the Achilles tendon followed by weightbearing within 4 weeks versus conservative treatment with weightbearing within 4 weeks. In addition, a secondary analysis was performed to compare the rerupture rates in patients who started weightbearing after 4 weeks. Seven randomized controlled trials published from 2001 to 2012, with 576 adult patients, were included. The primary outcome measure was the rerupture rate. The secondary outcomes were minor and major complications other than rerupture. In the early weightbearing group, 7 of 182 operatively treated patients (4%) experienced rerupture versus 21 of 176 of the conservatively treated patients (12%). A secondary analysis of the patients treated with late weightbearing showed a rerupture rate of 6% (7 of 108) for operatively treated patients versus 10% (11 of 110) for conservatively treated patients. The differences concerning the rerupture rate in both groups were not statistically significant. No differences were found in the occurrence of minor or major complications after early weightbearing in both patient groups. In conclusion, we found no difference in the rerupture rate between the surgically and nonsurgically treated patients followed by early weightbearing. Weightbearing after 4 weeks also resulted in no differences in the rupture rate in the surgical versus conservatively treated patients. However, surgical treatment was associated with a twofold greater complication rate than conservative treatment.

摘要

跟腱断裂采用手术治疗还是保守治疗仍存在争议。此外,康复方案会影响治疗结果。本荟萃分析的目的是比较跟腱手术修复后4周内负重与4周内保守治疗并负重后的再断裂率。此外,还进行了一项二次分析,以比较4周后开始负重的患者的再断裂率。纳入了2001年至2012年发表的7项随机对照试验,共576例成年患者。主要结局指标是再断裂率。次要结局是除再断裂外的轻微和严重并发症。在早期负重组中,182例接受手术治疗的患者中有7例(4%)发生再断裂,而176例接受保守治疗的患者中有21例(12%)发生再断裂。对晚期负重治疗患者的二次分析显示,手术治疗患者的再断裂率为6%(108例中的7例),而保守治疗患者的再断裂率为10%(110例中的11例)。两组再断裂率的差异无统计学意义。两组患者早期负重后轻微或严重并发症的发生率无差异。总之,我们发现早期负重后手术治疗和非手术治疗患者的再断裂率没有差异。4周后负重,手术治疗和保守治疗患者的断裂率也没有差异。然而,手术治疗的并发症发生率比保守治疗高两倍。

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