无金属过渡的三氟甲磺酸与不对称联芳基的氧化三氟甲基化反应。
Transition-metal-free oxidative trifluoromethylation of unsymmetrical biaryls with trifluoromethanesulfinate.
机构信息
Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.
出版信息
Chem Commun (Camb). 2013 Jun 18;49(48):5510-2. doi: 10.1039/c3cc41667d. Epub 2013 May 10.
PMID:23661223
Abstract
A transition-metal-free direct oxidative trifluoromethylation of unsymmetrical biaryls has been achieved by the simple combination of trifluoromethanesulfinate and phenyliodine bis(trifluoroacetate). The trifluoromethylation is selectively observed in the electron-rich arenes.
摘要
通过三氟甲磺酸亚砜和二(三氟乙酰基)碘苯的简单组合，实现了非对称联芳基的无过渡金属直接氧化三氟甲基化。三氟甲基化选择性地观察到富电子芳环中。
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