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自体胃肠道重建手术:肠移植的补充还是替代?

Autologous gastrointestinal reconstructive surgery: complement or alternative to intestinal transplantation.

机构信息

Neonatal Surgery Unit, Medical and Surgical Neonatal Department Bambino Gesù Children's Research Hospital, Rome, Italy.

出版信息

Curr Opin Organ Transplant. 2013 Jun;18(3):286-90. doi: 10.1097/MOT.0b013e3283607a16.

Abstract

PURPOSE OF REVIEW

Autologous intestinal reconstructive surgery has evolved over the past 3 decades from rescue to main surgical procedure in the multidisciplinary approach to short bowel syndrome (SBS) patients with intestinal failure. The purpose of this review is to clarify the actual place of intestinal reconstructive surgical techniques in the management of intestinal failure related to SBS and their relationship with intestinal transplantation.

RECENT FINDINGS

Recent reports from centers of excellence in intestinal rehabilitation underline the efficacy and safety of autologous intestinal reconstructive surgery in patients with SBS. Outcome parameters as survival, parenteral nutrition weaning, and clinical conditions were improved in SBS patients treated by gastrointestinal reconstructive surgery.

SUMMARY

Autologous intestinal reconstructive procedures are pivotal to achieve enteral autonomy in patients with intestinal failure related to SBS. They should be considered mutually supportive and not antagonistic to intestinal transplantation.

摘要

目的综述

在短肠综合征(SBS)合并肠衰竭患者的多学科治疗中,自体肠重建手术在过去 30 年中已从抢救性手术发展为主导性手术。本文旨在阐明肠重建手术技术在肠衰竭相关 SBS 管理中的实际地位及其与肠移植的关系。

最新发现

肠康复中心的最新报告强调了自体肠重建手术治疗 SBS 患者的安全性和有效性。胃肠道重建手术治疗的 SBS 患者的生存、肠外营养撤机和临床状况等结局参数均得到改善。

总结

自体肠重建术是实现与 SBS 相关肠衰竭患者肠内自主的关键。它们应该被认为是相互支持的,而不是与肠移植对抗。

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