Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
IEEE Trans Biomed Eng. 2013 Sep;60(9):2655-62. doi: 10.1109/TBME.2013.2262150. Epub 2013 May 13.
This paper describes a novel microbend fiber optic sensor system for respiratory monitoring and respiratory gating in the MRI environment. The system enables the noninvasive real-time monitoring and measurement of breathing rate and respiratory/body movement pattern of healthy subjects inside the MRI gantry, and has potential application in respiratory-gated image acquisition based on respiratory cues. The working principle behind this sensor is based on the microbending effect of an optical fiber on light transmission. The sensor system comprises of a 1.0-mm-thin graded-index multimode optical fiber-embedded plastic sensor mat, a photoelectronic transceiver, and a computer with a digital signal processing algorithm. In vitro testing showed that our sensor has a typical signal-to-noise ratio better than 28 dB. Clinical MRI trials conducted on 20 healthy human subjects showed good and comparable breathing rate detection (with an accuracy of ±2 bpm) and respiratory-gated image quality produced using the sensor system, with reference to current predicate hospital device/system. The MRI safe, ease of operation characteristics, low fabrication cost, and extra patient comfort offered by this system suggest its good potential in replacing predicate device/system and serve as a dual function in real-time respiratory monitoring and respiratory-gated image acquisition at the same time during MRI.
本文介绍了一种用于 MRI 环境中呼吸监测和呼吸门控的新型微弯光纤传感器系统。该系统能够在 MRI 磁体内部对健康受试者的呼吸频率和呼吸/身体运动模式进行非侵入式实时监测和测量,并有可能基于呼吸提示进行呼吸门控图像采集。该传感器的工作原理基于光纤对光传输的微弯效应。该传感器系统包括 1.0 毫米厚的渐变折射率多模光纤嵌入式塑料传感器垫、光电收发器以及带有数字信号处理算法的计算机。体外测试表明,我们的传感器具有典型的信噪比优于 28 dB。对 20 名健康人体进行的临床 MRI 试验表明,使用该传感器系统可以很好地检测呼吸率(精度为±2 bpm),并且可以产生具有可比性的呼吸门控图像质量,与当前的预测医院设备/系统相比。该系统具有 MRI 安全性、易于操作、制造成本低以及为患者提供额外舒适度等特点,表明其在替代预测设备/系统方面具有良好的潜力,并可同时在 MRI 期间实现实时呼吸监测和呼吸门控图像采集的双重功能。