波格尼亚病毒，一种在波兰的欧亚水鼩（Neomys fodiens）体内发现的新型汉坦病毒。
Boginia virus, a newfound hantavirus harbored by the Eurasian water shrew (Neomys fodiens) in Poland.
机构信息
Pacific Center for Emerging Infectious Diseases Research, John A, Burns School of Medicine, University of Hawaii at Manoa, 651 Ilalo Street, BSB320L, Honolulu, Hawaii 96813, USA.
出版信息
Virol J. 2013 May 22;10:160. doi: 10.1186/1743-422X-10-160.
BACKGROUND
Guided by decades-old reports of hantaviral antigens in the Eurasian common shrew (Sorex araneus) and the Eurasian water shrew (Neomys fodiens) in European Russia, we employed RT-PCR to analyze lung tissues of soricine shrews, captured in Boginia, Huta Dłutowska and Kurowice in central Poland during September 2010, 2011 and 2012.
FINDINGS
In addition to Seewis virus (SWSV), which had been previously found in Eurasian common shrews elsewhere in Europe, a genetically distinct hantavirus, designated Boginia virus (BOGV), was detected in Eurasian water shrews captured in each of the three villages. Phylogenetic analysis, using maximum likelihood and Bayesian methods, showed that BOGV formed a separate lineage distantly related to SWSV.
CONCLUSIONS
Although the pathogenic potential of BOGV and other recently identified shrew-borne hantaviruses is still unknown, clinicians should be vigilant for unusual febrile diseases and clinical syndromes occurring among individuals reporting exposures to shrews.
背景
受几十年前在欧洲俄罗斯的欧亚普通鼩鼱（Sorex araneus）和欧亚水鼩（Neomys fodiens）中发现汉坦病毒抗原的报告的指导，我们采用 RT-PCR 分析了 2010 年 9 月、2011 年和 2012 年在波兰中部的 Boginia、Huta Dłutowska 和 Kurowice 捕获的鼩鼱肺组织。
结果
除了先前在欧洲其他地方的欧亚普通鼩鼱中发现的 Seewis 病毒（SWSV）外，还在每个村庄捕获的欧亚水鼩中检测到一种遗传上不同的汉坦病毒，命名为 Boginia 病毒（BOGV）。最大似然和贝叶斯法的系统发育分析表明，BOGV 与 SWSV 形成了一个遥远相关的单独谱系。
结论
尽管 BOGV 和其他最近鉴定的鼩鼱携带的汉坦病毒的致病潜力尚不清楚，但临床医生应该警惕报告接触鼩鼱的个体中出现的不常见发热性疾病和临床综合征。
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