Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
J Ultrasound Med. 2013 Jun;32(6):1041-7. doi: 10.7863/ultra.32.6.1041.
The purpose of this study was to determine the sonographic performance in pathologically proven cases of nasopharyngeal carcinoma and its involvement in the parapharyngeal space.
The study included 58 patients being treated for suspected nasopharyngeal carcinoma detected by routine nasopharyngoscopy who underwent pathologic biopsy. Sonography was performed immediately thereafter with a convex array transducer in both the B-mode and color mode. Forty-five of the 58 patients (90 parapharyngeal spaces) in whom nasopharyngeal carcinoma was proved by both sonography and pathologic biopsy underwent preradiotherapy magnetic resonance imaging (MRI). The sonographic findings were compared to the pathologic findings. The sonographic findings of parapharyngeal space involvement were correlated with the MRI findings.
The normal anatomy of the nasopharynx and parapharyngeal space, nasopharyngeal carcinoma, and its relationship with the parapharyngeal space were well shown on sonography. The sensitivity of sonography for detection of nasopharyngeal carcinoma was 97.8%, and the specificity was 41.7%. The sonographic findings of parapharyngeal space involvement had a high degree of agreement with MRI (κ = 0.757; P < .001).
These promising initial data indicate that sonography may be a useful tool for diagnosing nasopharyngeal carcinoma and defining the relationship between the tumor and the parapharyngeal space.
本研究旨在确定经病理证实的鼻咽癌病例的超声表现及其在咽旁间隙的受累情况。
本研究纳入了 58 例因常规鼻咽镜检查发现疑似鼻咽癌而接受病理活检的患者。随后立即使用凸阵探头在 B 模式和彩色模式下进行超声检查。在经超声和病理活检证实为鼻咽癌的 58 例患者中（90 个咽旁间隙），有 45 例患者接受了放疗前磁共振成像（MRI）检查。将超声检查结果与病理结果进行比较。将咽旁间隙受累的超声表现与 MRI 结果进行相关性分析。
超声能很好地显示鼻咽部和咽旁间隙的正常解剖结构、鼻咽癌及其与咽旁间隙的关系。超声诊断鼻咽癌的敏感性为 97.8%，特异性为 41.7%。超声检查对咽旁间隙受累的显示与 MRI 具有高度一致性（κ=0.757；P<0.001）。
这些初步研究数据表明，超声检查可能是一种有用的工具，可用于诊断鼻咽癌，并确定肿瘤与咽旁间隙的关系。
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