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1 型糖尿病患者自我血糖监测的决定因素:巴西多中心研究。

Determinants of self-monitoring of blood glucose in patients with Type 1 diabetes: a multi-centre study in Brazil.

机构信息

Department of Internal Medicine, Diabetes Unit, State University Hospital of Rio de Janeiro, São Paulo, Brazil.

出版信息

Diabet Med. 2013 Oct;30(10):1255-62. doi: 10.1111/dme.12236. Epub 2013 Jul 13.

Abstract

AIM

The aim of this study was to determine the relationship between the daily frequency of self-monitoring of blood glucose and glycaemic control, demographic and socio-economic status in patients with Type 1 diabetes under routine clinical care in Brazil.

METHODS

This was a cross-sectional, multi-centre study conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. The data were obtained from 3176 patients, aged 22 ± 11.8 years, of whom 56.3% were female and 57.4% were Caucasian. The mean time since diabetes diagnosis was 11.7 ± 8.1 years.

RESULTS

The prevalence of self-monitoring of blood glucose was 88.5%. There was a significant increase in self-monitoring frequency associated with female gender, lower ages, more intensive diabetes management and higher socio-economic status. A correlation between HbA(1c) levels and the daily frequency of self-monitoring was observed (r(s) = -0.13; P = 0.001). The mean HbA1c levels were related to the daily frequency of self-monitoring (P < 0.001) without additional benefit to patients who performed self-monitoring more than four times daily (9.2, 11.2, 10.2,15.2 and 15% for one, two, three, four, five or more self-monitoring tests daily, respectively; P < 0.0001).

CONCLUSIONS

The majority of our patients (88.5%) performed three or more self-monitoring tests daily, with more frequent testing reported by females, younger patients, those on intensive insulin regimens and of higher socio-economic status. No additional benefit was found in patients who performed self-monitoring more than four times daily. The diabetes care team must improve patients' education regarding self-monitoring of blood glucose and its benefits.

摘要

目的

本研究旨在确定在巴西常规临床护理下,1 型糖尿病患者的自我血糖监测频率与血糖控制、人口统计学和社会经济状况之间的关系。

方法

这是一项横断面、多中心研究,于 2008 年 12 月至 2010 年 12 月在巴西 20 个城市的 28 家公立医院进行。研究数据来自 3176 名年龄为 22 ± 11.8 岁的患者,其中 56.3%为女性,57.4%为白种人。糖尿病诊断后的平均时间为 11.7 ± 8.1 年。

结果

自我血糖监测的患病率为 88.5%。女性、年龄较小、糖尿病管理较密集和社会经济地位较高与自我监测频率显著增加相关。观察到 HbA1c 水平与自我监测频率之间存在相关性(r(s) = -0.13;P = 0.001)。HbA1c 水平与自我监测频率相关(P < 0.001),但对每天进行 4 次以上自我监测的患者没有额外获益(分别为每天进行 1、2、3、4、5 次或更多次自我监测测试的患者的平均 HbA1c 水平为 9.2%、11.2%、10.2%、15.2%和 15%;P < 0.0001)。

结论

我们的大多数患者(88.5%)每天进行 3 次或更多次自我监测测试,女性、年轻患者、接受强化胰岛素治疗方案和社会经济地位较高的患者报告的测试频率更高。每天进行 4 次以上自我监测的患者没有发现额外获益。糖尿病护理团队必须改善患者对自我血糖监测及其益处的教育。

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