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大麦条纹花叶病毒:结构与烟草花叶病毒的关系。

Barley stripe mosaic virus: structure and relationship to the tobamoviruses.

机构信息

Department of Biological Sciences and Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA.

出版信息

Virology. 2013 Sep 1;443(2):265-70. doi: 10.1016/j.virol.2013.05.010. Epub 2013 May 29.

Abstract

Barley stripe mosaic virus (BSMV) is the type member of the genus Hordeivirus, rigid, rod-shaped viruses in the family Virgaviridae. We have used fiber diffraction and cryo-electron microscopy to determine the helical symmetry of BSMV to be 23.2 subunits per turn of the viral helix, and to obtain a low-resolution model of the virus by helical reconstruction methods. Features in the model support a structural relationship between the coat proteins of the hordeiviruses and the tobamoviruses.

摘要

大麦条纹花叶病毒(BSMV)是类病毒属的模式成员,是韧皮部病毒科的丝状病毒。我们已经使用纤维衍射和低温电子显微镜来确定 BSMV 的螺旋对称性为每圈病毒螺旋 23.2 个亚基,并通过螺旋重建方法获得病毒的低分辨率模型。模型中的特征支持类病毒和烟草花叶病毒的外壳蛋白之间的结构关系。

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