在法国的巴氏金蝠中分离到博凯里欧文病毒。
Isolation of Bokeloh bat lyssavirus in Myotis nattereri in France.
机构信息
Anses, Laboratory for Rabies and Wildlife, European Union Reference Laboratory for rabies, European Union Reference Laboratory for rabies serology, OIE Reference Laboratory for rabies, WHO Collaborating centre for research and management in zoonoses control, Technopole agricole et veterinaire, BP 40009, 54 220, Malzéville Cedex, France,
出版信息
Arch Virol. 2013 Nov;158(11):2333-40. doi: 10.1007/s00705-013-1747-y. Epub 2013 Jun 12.
Bokeloh bat lyssavirus (BBLV) was found in Myotis nattereri for the first time in northeastern France in July 2012. The complete genome sequence of the virus from the infected Natterer's bat was determined by whole-genome sequencing and compared to that of the first BBLV strain isolated in 2010 in Germany and with those of all currently identified lyssaviruses. The French isolate [KC169985] showed 98.7 % nucleotide sequence identity to the German BBLV strain [JF311903]. Several organs of the infected French bat were examined by classical rabies diagnostic methods: fluorescent antibody test, cell culture inoculation test and RT-qPCR. Antigen, infectious virus and high viral RNA levels were found in both the brain and salivary glands. Traces of genomic RNA were detected in the bladder, kidney and lung tissue. The results of an investigation of the distribution of lyssaviruses with the detection of infectious virus in the salivary glands suggest a possible mode of transmission of the virus.
博氏梭形螺旋体病毒（BBLV）于 2012 年 7 月在法国东北部的 Myotis nattereri 中首次被发现。通过全基因组测序确定了来自受感染的 Natterer 蝙蝠的病毒的完整基因组序列，并与 2010 年在德国分离的第一个 BBLV 株以及所有目前鉴定的狂犬病病毒进行了比较。法国分离株 [KC169985] 与德国 BBLV 株 [JF311903] 的核苷酸序列同一性为 98.7%。用经典的狂犬病诊断方法对受感染的法国蝙蝠的几个器官进行了检查：荧光抗体试验、细胞培养接种试验和 RT-qPCR。在大脑和唾液腺中均发现了抗原、感染性病毒和高病毒 RNA 水平。在膀胱、肾脏和肺部组织中检测到基因组 RNA 的痕迹。通过检测唾液腺中的传染性病毒对狂犬病病毒分布的调查结果表明，该病毒可能存在传播方式。
Zotero 插件