特纳综合征患者的超声特征。

Turner syndrome patients' ultrasound profile.

机构信息

Internal Medicine Department, Hospital Clementino Fraga Filho (HUCFF) and Instituto de Puericultura e Pediatria Martagão Gesteira (IPPMG), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

出版信息

Gynecol Endocrinol. 2013 Jul;29(7):704-6. doi: 10.3109/09513590.2013.797391.

DOI:10.3109/09513590.2013.797391

PMID:23772782

Abstract

OBJECTIVE

Evaluate the uterus and ovary by ultrasonography, considering the genotype, pubertal development and hormonal levels.

MATERIALS AND METHODS

Cross-sectional study of 53 (7-53 years old) patients with Turner syndrome considering pubertal development by Tanner stage, puberty induced or not and the ultrasound examination.

RESULTS

The patients were 10 prepubertal and 43 with pubertal signs. Uterus was found adequate in 12 (57.1%) patients and all had spontaneous puberty. Hypoplasic uterus was found in all prepubertal patients and in 28 (52.8%) patients pubescent. The ovaries were visualized bilaterally in 32 (60%) patients and unilaterally in 15 (27.7%). Ovaries were appropriate bilaterally in eight (15.1%). In pubertal patients, the average volume being significantly higher in those with spontaneous puberty (p = 0.04 and 0.03, respectively). We found no significant difference in uterine volume, when considered estrogen route and karyotype.

CONCLUSION

The ultrasonographic pattern in patients with spontaneous puberty without secondary failure was appropriate. The karyotype and the route estrogen therapy were not related to the standard of ultrasound study of the uterus and ovary.

摘要

目的

通过超声检查评估特纳综合征患者的子宫和卵巢，同时考虑基因型、青春期发育和激素水平。

材料与方法

本研究为回顾性病例分析，共纳入 53 例特纳综合征患者（年龄 7-53 岁），根据 Tanner 分期评估青春期发育情况，分为青春期启动和未启动组，并进行超声检查。

结果

患者中 10 例为青春期前，43 例有青春期表现。12 例（57.1%）患者子宫大小正常，且均有自发青春期启动。所有青春期前患者及 28 例（52.8%）青春期患者子宫均为幼稚型。32 例（60%）患者双侧卵巢可见，15 例（27.7%）患者单侧卵巢可见。8 例（15.1%）患者双侧卵巢大小正常。在青春期患者中，自发青春期启动患者的卵巢平均体积明显高于继发青春期启动失败患者（p = 0.04 和 0.03）。我们发现，子宫体积与雌激素途径和核型无明显相关性。