Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology (CSIR-IICT), Tarnaka, Hyderabad-500 607, India.
Chem Commun (Camb). 2013 Jul 28;49(59):6686-8. doi: 10.1039/c3cc42381f.
Direct access to unsymmetrical urea derivatives via copper catalysed C-H/N-H coupling of formamides with amines has been developed at room temperature. This protocol is also applied to the synthesis of chiral urea derivatives.
在室温条件下，通过铜催化的甲酰胺与胺的 C-H/N-H 偶联反应，可直接得到不对称脲衍生物。该方法还可用于手性脲衍生物的合成。
