Ashtari Fereshteh, Jamshidi Fatemeh, Shoormasti Raheleh Shokouhi, Pourpak Zahra, Akbari Mojtaba, Zandieh Faiborz
Department of Neurology, Isfahan Neuroscience Research Centre, Isfahan University of Medical Science, Isfahan, Iran.
Int J Prev Med. 2013 May;4(Suppl 2):S185-8.
The effect of nutrition in the course of multiple sclerosis (MS) is a topic of great interest. The present study was aimed to evaluate the immunoglobin E (IgE) against egg and fish in MS patients compared to healthy controls.
Between March 2012 and July 2012, 48 MS patients were selected and compared with 48 healthy subjects to assess the frequency of IgE against egg and fish in MS patients compared to healthy control. Fish and Egg specific IgE was determined by Immuno CAP. Sex and the frequency of specific IgE were compared between study groups by Chi-square test.
Total of 96 subjects was assessed (22% male and 78% female). The mean age of the study subjects was 30.8 ± 6.6 years. Mean age of case and control groups was 30.7 (±6.9) versus 30.9 ± 6.3, respectively (P = 0.83). There were no detection of egg and fish specific IgE in serum of MS patients and healthy subjects.
IgE allergy against fish and egg may be very unlikely to affect MS course.
营养在多发性硬化症(MS)病程中的作用是一个备受关注的话题。本研究旨在评估与健康对照相比,MS患者中针对鸡蛋和鱼类的免疫球蛋白E(IgE)情况。
在2012年3月至2012年7月期间,选取48例MS患者,并与48例健康受试者进行比较,以评估与健康对照相比,MS患者中针对鸡蛋和鱼类的IgE频率。通过免疫CAP法测定鱼类和鸡蛋特异性IgE。采用卡方检验比较研究组之间的性别和特异性IgE频率。
共评估了96名受试者(22%为男性,78%为女性)。研究对象的平均年龄为30.8±6.6岁。病例组和对照组的平均年龄分别为30.7(±6.9)岁和30.9±6.3岁(P = 0.83)。在MS患者和健康受试者的血清中均未检测到鸡蛋和鱼类特异性IgE。
对鱼类和鸡蛋的IgE过敏极不可能影响MS病程。