Igor Simanic, Mirko Teofilovski, Dalibor Paspalj, Milutin Radotic, Dusica Djordjevic, Vladimir Zivkovic, Vladimir Jakovljevic
Specialized Hospital for Rehabilitation and Orthopedic Prosthetics, Belgrade, Serbia.
Undersea Hyperb Med. 2013 May-Jun;40(3):289-97.
The purpose of the study was to assess the effects of hyperbaric oxygen (HBO2) therapy on prosthetic rehabilitation of patients with unilateral lower limb amputation. Narang's scale,the Locomotor Capabilities Index and the two-minute walk test were used to assess functional abilities of amputees on the admission and on discharge from hospital. We also kept records of some clinical parameters whose improvement enables better mobility of patients: thigh and lower leg girth, strength of amputation stump, existence of amputation stump contracture, existence of some other complications on amputation stump, blood oxygenation and pulse palpation. Our results show that hyperbaric oxygenation accelerates prosthetic rehabilitation of lower limb amputees. HBO2-treated patients were discharged from the hospital faster than the controls (hospitalized for 133.2 +/- 54.87 days vs. 158.36 +/- 53.05 days), they had improved arterial Hb saturation (97.40 +/- 3.51% vs. 94.74 +/- 3.28 %) and pulse palpability (pulse palpable in 27 vs. 18 subjects), less complications of the amputation stump (complications present in 24 vs. 30 subjects), greater healthy leg thigh girth (50.75 +/- 3.96 cm vs. 48.90 +/- 2.59 cm), stronger amputation stump (mark 3.90 +/- 0.54 vs. 3.33 +/- 0.47) and better functional abilities as measured by adapted Narang's scale (category 3.43 +/- 1.30 vs. 4.10 +/- 1.12) and locomotor capabilities index (score 38.06 +/- 10.90 vs. 33.16 +/- 8.80). These findings highlight the increasing validity of this procedure after limb amputation, which should be confirmed by further research in multicenter studies involving a larger number of respondents.
本研究的目的是评估高压氧(HBO₂)疗法对单侧下肢截肢患者假体康复的影响。采用纳朗量表、运动能力指数和两分钟步行试验来评估截肢患者入院时和出院时的功能能力。我们还记录了一些临床参数,这些参数的改善有助于患者更好地活动:大腿和小腿周长、截肢残端力量、截肢残端挛缩的存在情况、截肢残端是否存在其他并发症、血氧饱和度和脉搏触诊。我们的结果表明,高压氧疗可加速下肢截肢患者的假体康复。接受HBO₂治疗的患者比对照组出院更快(住院时间分别为133.2±54.87天和158.36±53.05天);他们的动脉血红蛋白饱和度有所提高(分别为97.40±3.51%和94.74±3.28%),脉搏可触及性更好(脉搏可触及的患者分别为27例和18例),截肢残端并发症更少(出现并发症的患者分别为24例和30例),健侧大腿周长更大(分别为50.75±3.96厘米和48.90±2.59厘米),截肢残端更强壮(评分为3.90±0.54和3.33±0.47),并且根据改良的纳朗量表(类别为3.43±1.30和4.10±1.12)和运动能力指数(评分为38.06±10.90和33.16±8.80)测量,功能能力更好。这些发现凸显了该治疗方法在肢体截肢后越来越高的有效性,这一点应在涉及更多受试者的多中心研究中通过进一步研究加以证实。