Sharma Shruti, Agrawal Usha, Gupta Pooja, Bhatnagar Amar, Jairajpuri Zeeba
Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Ann Saudi Med. 2013 May-Jun;33(3):304-6. doi: 10.5144/0256-4947.2013.304.
The simultaneous presence of two disparate neoplasms occurring in the same specimen has been well documented, albeit uncommonly. The juxtaposition of malignant melanoma (MM) and basal cell carcinoma (BCC) as collision tumors has been rarely reported, with most cases describing melanoma in situ and BCC. We report a case of a 20-year-old male presenting with three papillomatous growths on the face, localized over the left frontotemporal region, below the right eye and over the right eyebrow. On histopathology and immunohistochemistry the lesions were diagnosed as pigmented MM and BCC. MM and BCC presenting at different sites on the face in the same patient along with a focus of metastasis in the same anatomical region as the primary tumor is quite rare. To the best of our knowledge this is the first report of such a case.
同一标本中同时存在两种不同肿瘤的情况已有充分记录,尽管并不常见。恶性黑色素瘤(MM)和基底细胞癌(BCC)作为碰撞瘤并存的情况鲜有报道,大多数病例描述的是原位黑色素瘤和基底细胞癌。我们报告一例20岁男性患者,面部出现三个乳头状肿物,分别位于左额颞部、右眼下及右眉上方。经组织病理学和免疫组化检查,病变被诊断为色素性MM和BCC。同一患者面部不同部位同时出现MM和BCC,且在与原发肿瘤相同的解剖区域有转移灶,这种情况非常罕见。据我们所知,这是首例此类病例报告。