Egea Gustavo, Serra-Peinado Carla, Salcedo-Sicilia Laia, Gutiérrez-Martínez Enric
Departament de Biologia Cel·lular, Immunologia i Neurociències, Facultat de Medicina, Universitat de Barcelona, C/Casanova, 143, 08036, Barcelona, Spain.
Histochem Cell Biol. 2013 Sep;140(3):347-60. doi: 10.1007/s00418-013-1115-8. Epub 2013 Jun 27.
The organization, assembly and remodeling of the actin cytoskeleton provide force and tracks for a variety of (endo)membrane-associated events such as membrane trafficking. This review illustrates in different cellular models how actin and many of its numerous binding and regulatory proteins (actin and co-workers) participate in the structural organization of the Golgi apparatus and in trafficking-associated processes such as sorting, biogenesis and motion of Golgi-derived transport carriers.
肌动蛋白细胞骨架的组织、组装和重塑为各种(内)膜相关事件(如膜运输)提供了力量和轨道。本综述在不同的细胞模型中阐述了肌动蛋白及其众多结合和调节蛋白(肌动蛋白及其协同因子)如何参与高尔基体的结构组织以及与运输相关的过程,如高尔基体衍生运输载体的分选、生物发生和运动。