Jain Rajendra Kumar, Padmanabhan T N C, Chitnis Nishad
Senior Consultant Interventional Cardiologist, Director, Department of Cardiology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad, India.
Indian Heart J. 2013 May-Jun;65(3):264-8. doi: 10.1016/j.ihj.2013.04.023. Epub 2013 Apr 10.
The objective of this case series is to identify and define causes of failure of Szabo technique in rapid-exchange monorail system for ostial lesions.
From March 2009 to March 2011, 42 patients with an ostial lesion were treated percutaneously at our institution using Szabo technique in a monorail stent system. All patients received unfractionated heparin during intervention. Loading dose of clopidogrel, followed by clopidogrel and aspirin was administered. In 57% of patients, drug-eluting stents were used and in 42.8% patients bare metal stents. The stent was advanced over both wires, the target wire and the anchor wire. The anchor wire, which was passed through the proximal trailing strut of the stent helps to achieve precise stenting. The procedure was considered to be successful if stent was placed precisely covering the lesion and without stent loss or anchor wire prolapsing. Of the total 42 patients, the procedure was successful in 33, while failed in 9. Majority of failures were due to wire entanglement, which was fixed successfully in 3 cases by removing and reinserting the anchor wire. Out of other three failures, in one stent dislodgment occurred, stent could not cross the lesion in one and in another anchor wire got looped and prolapsed into target vessel.
This case series shows that the Szabo technique, in spite of some difficulties like wire entanglement, stent dislodgement and resistance during stent advancement, is a simple and feasible method for treating variety of ostial lesions precisely compared to conventional angioplasty.
本病例系列的目的是识别并明确在快速交换单轨系统中治疗开口病变时Szabo技术失败的原因。
2009年3月至2011年3月,在我们机构对42例开口病变患者采用单轨支架系统中的Szabo技术进行了经皮治疗。所有患者在介入过程中均接受了普通肝素治疗。给予氯吡格雷负荷剂量,随后给予氯吡格雷和阿司匹林。57%的患者使用了药物洗脱支架,42.8%的患者使用了裸金属支架。支架通过两根导丝推进,即目标导丝和锚定导丝。穿过支架近端尾端支柱的锚定导丝有助于实现精确支架置入。如果支架精确放置覆盖病变且无支架丢失或锚定导丝脱垂,则该操作被认为是成功的。在总共42例患者中,33例操作成功,9例失败。大多数失败是由于导丝缠绕,其中3例通过移除并重新插入锚定导丝成功解决。在其他三例失败中,一例发生支架移位,一例支架无法穿过病变,另一例锚定导丝成环并脱垂至目标血管。
本病例系列表明,尽管Szabo技术存在一些困难,如导丝缠绕、支架移位和支架推进过程中的阻力,但与传统血管成形术相比,它是一种精确治疗各种开口病变的简单可行方法。