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膳食补充剂与牙科常用药物的相互作用。

Dietary supplement interactions with medications used commonly in dentistry.

机构信息

Kalispell Regional Medical Center, Kalispell, Mont., USA.

出版信息

J Am Dent Assoc. 2013 Jul;144(7):787-94. doi: 10.14219/jada.archive.2013.0188.

Abstract

BACKGROUND

Because nearly 70 percent of prescription drug users do not discuss their dietary supplement use with their health care providers, clinicians must be proactive in questioning patients about their use of these agents. A complete and accurate pharmacological history will help clinicians avoid potential interactions between dietary supplements and drugs.

METHODS

The authors reviewed the literature regarding interactions between popular dietary supplements and medications used commonly in dentistry. They used clinical databases and decision support tools to classify interactions according to their level of risk for the patient. The authors address the interactions of greatest clinical concern with a high-quality evidence-based foundation in either randomized controlled clinical trials or meta-analyses.

CONCLUSIONS

Provided that patients are not taking ginkgo, St. John's wort, evening primrose or valerian, oral health care providers can prescribe or administer any of the medications used commonly in dentistry without concern about possible dietary supplement-drug interactions.

PRACTICAL IMPLICATIONS

Recognition and avoidance of potential interactions between dietary supplements and drugs will help clinicians optimize treatment while emphasizing patients' safety.

摘要

背景

由于近 70%的处方药使用者不会与他们的医疗保健提供者讨论他们的膳食补充剂使用情况,因此临床医生必须主动询问患者他们使用这些药物的情况。完整、准确的药理学病史将有助于临床医生避免膳食补充剂和药物之间潜在的相互作用。

方法

作者回顾了关于常见牙科药物与流行膳食补充剂之间相互作用的文献。他们使用临床数据库和决策支持工具根据患者的风险水平对相互作用进行分类。作者针对最受临床关注的相互作用,以随机对照临床试验或荟萃分析为基础,提供了高质量的循证依据。

结论

如果患者不服用银杏、贯叶连翘、月见草或缬草,口腔保健提供者可以在不担心可能的膳食补充剂-药物相互作用的情况下开处方或使用牙科中常用的任何药物。

实际意义

识别和避免膳食补充剂与药物之间的潜在相互作用将有助于临床医生在强调患者安全的同时优化治疗。

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