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瘤样脱髓鞘病变:一种导致同向性偏盲自发缓解的罕见病因。

Tumefactive demyelination: an unusual cause of a spontaneously resolving homonymous hemianopia.

作者信息

Dwivedi R A, Dwivedi R E, Durnian J M, Young C A

机构信息

Royal Liverpool & Broadgreen University Hospitals Trust, Liverpool, UK.

出版信息

BMJ Case Rep. 2013 Jun 21;2013:bcr2013009363. doi: 10.1136/bcr-2013-009363.

Abstract

A 21-year-old man presented to eye casualty complaining of altered vision associated with headache and vomiting upon waking. Clinical examination was unremarkable except for a right-sided homonymous hemianopia. The MRI scan of the brain revealed a space occupying lesion within the occipital lobe and MR spectroscopy highlighted this to be inflammatory in nature, most likely a tumefactive demyelinating lesion (TDL). Lumbar puncture displayed positive oligoclonal bands. The patient was managed conservatively and made a full recovery, with normal visual fields recorded after a 3 month follow-up. This is a case of a TDL manifesting itself as an unusual cause of homonymous hemianopia; misdiagnosis of TDL is common and potentially damaging to the patient.

摘要

一名21岁男性因晨起后视力改变伴头痛、呕吐前往眼科急诊就诊。除右侧同向性偏盲外,临床检查无异常。脑部MRI扫描显示枕叶有占位性病变,磁共振波谱分析表明该病变本质上是炎性的,很可能是瘤样脱髓鞘病变(TDL)。腰椎穿刺显示寡克隆带阳性。患者接受保守治疗并完全康复,随访3个月后视野恢复正常。这是一例TDL表现为同向性偏盲罕见病因的病例;TDL的误诊很常见,且可能对患者造成损害。

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