Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, 167 Ashley Avenue, Suite 301, Charleston, SC 29425, United States.
Resuscitation. 2013 Nov;84(11):1585-90. doi: 10.1016/j.resuscitation.2013.06.014. Epub 2013 Jun 28.
Quality chest compressions (CC) are the most important factor in successful cardiopulmonary resuscitation. Adjustment of CC based upon an invasive arterial blood pressure (ABP) display would be theoretically beneficial. Additionally, having one compressor present for longer than a 2-min cycle with an ABP display may allow for a learning process to further maximize CC. Accordingly, we tested the hypothesis that CC can be improved with a real-time display of invasively measured blood pressure and with an unchanged, physically fit compressor.
A manikin was attached to an ABP display derived from a hemodynamic model responding to parameters of CC rate, depth, and compression-decompression ratio. The area under the blood pressure curve over time (AUC) was used for data analysis. Each participant (N=20) performed 4 CPR sessions: (1) No ABP display, exchange of compressor every 2 min; (2) ABP display, exchange of compressor every 2 min; (3) no ABP display, no exchange of the compressor; (4) ABP display, no exchange of the compressor. Data were analyzed by ANOVA. Significance was set at a p-value<0.05.
The average AUC for cycles without ABP display was 5201 mm Hgs (95% confidence interval (CI) of 4804-5597 mm Hgs), and for cycles with ABP display 6110 mm Hgs (95% CI of 5715-6507 mm Hgs) (p<0.0001). The average AUC increase with ABP display for each participant was 20.2±17.4% 95 CI (p<0.0001).
Our study confirms the hypothesis that a real-time display of simulated ABP during CPR that responds to participant performance improves achieved and sustained ABP. However, without any real-time visual feedback, even fit compressors demonstrated degradation of CC quality.
高质量的胸外按压(CC)是心肺复苏成功的最重要因素。根据有创动脉血压(ABP)显示调整 CC 理论上是有益的。此外,有一名按压者在有 ABP 显示的情况下进行超过 2 分钟的按压周期,可能会有一个学习过程,以进一步最大限度地提高 CC。因此,我们测试了这样一个假设,即通过实时显示有创测量的血压和不变的、身体健康的按压者,可以改善 CC。
一个模拟人被连接到一个源自血流动力学模型的 ABP 显示器,该模型对 CC 频率、深度和压缩-减压比的参数做出反应。分析数据时使用时间上的血压曲线下面积(AUC)。每位参与者(N=20)进行了 4 次 CPR 课程:(1)没有 ABP 显示,每 2 分钟更换按压者;(2)ABP 显示,每 2 分钟更换按压者;(3)没有 ABP 显示,不更换按压者;(4)ABP 显示,不更换按压者。采用方差分析对数据进行分析。显著性设定为 p 值<0.05。
没有 ABP 显示的循环的平均 AUC 为 5201mm Hgs(95%置信区间(CI)为 4804-5597mm Hgs),有 ABP 显示的循环的平均 AUC 为 6110mm Hgs(95% CI 为 5715-6507mm Hgs)(p<0.0001)。每位参与者的 ABP 显示时的 AUC 平均增加 20.2±17.4% 95 CI(p<0.0001)。
我们的研究证实了这样一个假设,即在 CPR 期间实时显示模拟 ABP,对参与者的表现做出反应,可以提高达到的和维持的 ABP。然而,即使是健康的按压者,如果没有实时的视觉反馈,CC 质量也会下降。