Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Br J Cancer. 2013 Jul 9;109(1):35-41. doi: 10.1038/bjc.2013.322. Epub 2013 Jul 2.
There was concern that failure to screen women aged 20-24 years would increase the number of cancers or advanced cancers in women aged 20-29 years. We describe the characteristics of women diagnosed with cervical cancer in England aged 20-29 years and examine the association between the period of diagnosis, screening history and FIGO stage.
We used data on 1800 women diagnosed with cervical cancer between April 2007 and March 2012 at age 20-29 from the National Audit of Invasive Cervical Cancers.
The majority of cancers (995, or 62% of those with known stage) were stage 1A. Cancer at age 20-24 years was rare (12% of those aged 20-29 years), when compared with age 25 (24%) and age 26-29 years (63%); however, cancers in women aged 20-24 years tended to be more advanced and were more often of a rare histological type. For 59% of women under age 30, the cervical cancer was screen detected, most of them (61%) as a result of their first screening test. A three-fold increase in the number of cancers diagnosed at age 25 years was seen since the start of the study period.
Cervical cancer at age 20-24 years is rare. Most cancers in women under age 30 years are screen detected as microinvasive cancer.
有人担心，如果不筛查 20-24 岁的女性，会导致 20-29 岁女性的癌症或晚期癌症病例增加。我们描述了英格兰 20-29 岁诊断为宫颈癌的女性的特征，并研究了诊断时期、筛查史和 FIGO 分期之间的关系。
我们使用了 2007 年 4 月至 2012 年 3 月期间年龄在 20-29 岁之间的 1800 名宫颈癌患者的全国性侵袭性宫颈癌普查数据。
大多数癌症（995 例，已知分期的患者中占 62%）为 1A 期。与 25 岁（24%）和 26-29 岁（63%）相比，20-24 岁年龄组的癌症（占 29 岁以下的 12%）很少见，但这些癌症往往更为晚期，且更常为罕见的组织学类型。在 30 岁以下的女性中，有 59%的宫颈癌是通过筛查发现的，其中大多数（61%）是通过首次筛查检测发现的。自研究开始以来，25 岁时诊断出的癌症数量增加了三倍。
20-24 岁的宫颈癌很少见。大多数 30 岁以下女性的癌症是通过筛查发现的，为微浸润性癌。
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