HIV患者的疼痛、心理症状与处方药滥用：文献综述
Pain, psychological symptoms and prescription drug misuse in HIV: A literature review.
作者信息
Tsao Jennie C I, Plankey Michael W, Young Mary A
机构信息
Pediatric Pain Program, Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California.
出版信息
J Pain Manag. 2012 Apr;5(2):111-118.
BACKGROUND
Pain is a common problem among persons living with HIV. In this population, pain often co-occurs with psychological symptoms, as well as illicit drug abuse. Recently, the misuse of prescription drugs, including the misuse of opioid medications for pain relief, has emerged as a significant public health problem. The purpose of this article is to review the literature on the associations among pain, illicit drug use, and symptoms of depression and anxiety in the misuse of prescription medications in HIV disease.
RESULTS AND CONCLUSIONS
Although relatively little attention has centered on the management of pain, psychological symptoms and other distressing, yet treatable symptoms in HIV, the fact that drug abuse behaviors now constitute a primary risk factor for HIV infection requires a shift in focus for clinicians and researchers alike. There is currently little agreement regarding the medical provision of opioids to persons with a history of illicit drug use. Thus, additional research is required to ensure adequate treatment of pain and psychological symptoms in persons living with HIV while minimizing the risk of prescription drug misuse.
背景
疼痛是艾滋病毒感染者中的常见问题。在这一人群中，疼痛常与心理症状以及非法药物滥用同时出现。最近，包括滥用阿片类药物缓解疼痛在内的处方药滥用已成为一个重大的公共卫生问题。本文旨在综述关于艾滋病毒疾病中处方药滥用时疼痛、非法药物使用与抑郁和焦虑症状之间关联的文献。
结果与结论
尽管相对较少关注艾滋病毒感染者疼痛、心理症状及其他令人痛苦但可治疗症状的管理，但药物滥用行为现已成为艾滋病毒感染的主要危险因素这一事实要求临床医生和研究人员都转变关注重点。目前对于有非法药物使用史的人使用阿片类药物的医疗规定几乎没有共识。因此，需要更多研究以确保艾滋病毒感染者的疼痛和心理症状得到充分治疗，同时将处方药滥用风险降至最低。
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