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经口机器人辅助侧方口咽切除术与传统手术治疗T1至T3期扁桃体癌的肿瘤学和功能结局比较

Comparison of oncologic and functional outcomes after transoral robotic lateral oropharyngectomy versus conventional surgery for T1 to T3 tonsillar cancer.

作者信息

Lee Sei Young, Park Young Min, Byeon Hyung Kwon, Choi Eun Chang, Kim Se-Heon

机构信息

Department of Otorhinolaryngology, Chung-Ang University College of Medicine, Seoul, Korea.

出版信息

Head Neck. 2014 Aug;36(8):1138-45. doi: 10.1002/hed.23424. Epub 2013 Oct 17.

Abstract

BACKGROUND

We performed transoral robotic surgery (TORS) or conventional surgery via a transoral or mandibulotomy approach in patients with tonsillar cancer and prospectively analyzed the oncologic outcomes and functional recovery of the 3 groups.

METHODS

Between May 2008 and October 2011, 57 patients were enrolled in this prospective study.

RESULTS

Although there was no significant difference in the survival rate of the TORS group (100%) and the conventional surgery group (96.7%), a higher rate of margin negativity was observed in the TORS group, especially in cases in which the tumor extends inferiorly. Patients who received TORS or conventional transoral procedures showed more rapid recovery of swallowing, shorter hospitalization, and shorter operation time than the mandibulotomy group.

CONCLUSION

Despite the weakness of this nonrandomized trial and the differences in T classification, TORS seemed to have distinct advantages over conventional transoral surgery and other conventional open surgery, but further studies are needed.

摘要

背景

我们对扁桃体癌患者采用经口机器人手术(TORS)或经口或下颌骨切开术式的传统手术,并对三组患者的肿瘤学结局和功能恢复情况进行了前瞻性分析。

方法

2008年5月至2011年10月期间,57例患者纳入了这项前瞻性研究。

结果

尽管TORS组(100%)和传统手术组(96.7%)的生存率无显著差异,但TORS组的切缘阴性率更高,尤其是肿瘤向下扩展的病例。接受TORS或传统经口手术的患者吞咽恢复更快,住院时间更短,手术时间比下颌骨切开术组更短。

结论

尽管这项非随机试验存在局限性且T分类存在差异,但TORS似乎比传统经口手术和其他传统开放手术具有明显优势,但仍需要进一步研究。

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