Li Fang-Cai, Cui Ai-Li, Zhang Hong, Deng Li, Xiang Xing-Yu, Huang Yi-Wei, Li Wei-Chao, Liu Yun-zhi
Hunan Provinial Center for Disease Control and Prevention, Changsha 410005, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2013 Feb;27(1):25-7.
To be acquainted with genetic characteristics and variation of mumps virus strains circulating in Hunan province.
Mumps virus (MV) strains were isolated using Vero/ SLAM cells. The small hydrophobic protein (SH) genes of MV isolates were sequenced, and the sequences were analysed phylogenetically between the isolated strains and other reference mumps strains.
4 mumps virus strains were isolated from 16 specimens collected in 2011 from different regions of Hunan province. The genotype of isolated strains were supposed to be F type.
Genotype F is the main genotype of circulating strains in Hunan province in 2011 and there is no variation between genotype.
了解湖南省流行的腮腺炎病毒株的基因特征及变异情况。
采用Vero/SLAM细胞分离腮腺炎病毒(MV)株。对MV分离株的小疏水蛋白(SH)基因进行测序,并对分离株与其他参考腮腺炎毒株进行系统发育分析。
从2011年湖南省不同地区采集的16份标本中分离出4株腮腺炎病毒株。分离株的基因型推测为F型。
F基因型是2011年湖南省流行毒株的主要基因型,且基因型间无变异。